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Tegretol and Rickets - a phase IV clinical study of FDA data

Summary:

Rickets is reported as a side effect among people who take Tegretol (carbamazepine), especially for people who are female, 50-59 old, have been taking the drug for < 1 month also take Keppra, and have Partial seizures.

The phase IV clinical study analyzes which people have Rickets when taking Tegretol. It is created by eHealthMe based on reports of 44,100 people who have side effects when taking Tegretol from the FDA, and is updated regularly.

What is Tegretol?

Tegretol has active ingredients of carbamazepine. It is often used in epilepsy. eHealthMe is studying from 45,969 Tegretol users. Check the latest studies of Tegretol.

What is Rickets?

Rickets (softening of bones) is found to be associated with 1,094 drugs and 1,457 conditions by eHealthMe. Check the latest studies of Rickets.

On Jul, 13, 2026

44,100 people reported to have side effects when taking Tegretol.
Among them, 62 people (0.14%) have Rickets.

Could Tegretol cause Rickets?

Among these 62 people:

How long have people been on Tegretol when they have Rickets? *

  • < 1 month: 50.0 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 33.33 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 16.67 %

What is the gender of people who have Rickets when taking Tegretol? *

  • female: 75.41 %
  • male: 24.59 %

What is the age of people who have Rickets when taking Tegretol? *

  • 0-1: 0.0 %
  • 2-9: 10.2 %
  • 10-19: 20.41 %
  • 20-29: 6.12 %
  • 30-39: 16.33 %
  • 40-49: 14.29 %
  • 50-59: 20.41 %
  • 60+: 12.24 %

What are other drugs people take besides Tegretol? *

  1. Keppra: 8 people, 12.90%
  2. Depakene: 7 people, 11.29%
  3. Fosamax: 6 people, 9.68%
  4. Vitamin D: 4 people, 6.45%
  5. Depakote: 4 people, 6.45%
  6. Pantoprazole: 3 people, 4.84%
  7. Ativan: 3 people, 4.84%
  8. Monurol: 3 people, 4.84%
  9. Rocaltrol: 3 people, 4.84%
  10. Mysoline: 3 people, 4.84%

What are other side effects people have besides Rickets? *

  1. Hypocalcaemia (levels of calcium in blood serum are abnormally low): 13 people, 20.97%
  2. Bone Density Decreased: 9 people, 14.52%
  3. Back Pain: 7 people, 11.29%
  4. Hypophosphataemia (electrolyte disturbance in which there is an abnormally low level of phosphate in the blood): 7 people, 11.29%
  5. Fatigue (feeling of tiredness): 6 people, 9.68%
  6. Osteomalacia (softening of the bones due to a lack of vitamin d): 6 people, 9.68%
  7. Blood Parathyroid Hormone Increased: 6 people, 9.68%
  8. Pain: 6 people, 9.68%
  9. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 5 people, 8.06%
  10. Blood Calcium Decreased: 5 people, 8.06%

What are the existing conditions these people have? *

  1. Diabetes: 4 people, 6.45%
  2. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 4 people, 6.45%
  3. Partial Seizures (seizures which affect only a part of the brain at onset): 4 people, 6.45%
  4. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 3 people, 4.84%
  5. Nausea (feeling of having an urge to vomit): 3 people, 4.84%
  6. Bone Density Decreased: 3 people, 4.84%
  7. Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 3 people, 4.84%
  8. Gastrointestinal Haemorrhage (bleeding gastrointestinal tract): 3 people, 4.84%
  9. Secondary Progressive Multiple Sclerosis (a stage of ms which comes after relapsing remitting ms in many cases): 3 people, 4.84%
  10. Adverse Event: 3 people, 4.84%

* Approximation only. Some reports may have incomplete information.

Do you take Tegretol and have Rickets?

- Check whether Rickets is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Tegretol:

Rickets treatments and more:

How severe was Rickets and when was it recovered:

Expand to all the drugs that have ingredients of carbamazepine:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Tegretol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Rickets:

Browse all the conditions that are associated with Rickets:

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on carbamazepine (the active ingredients of Tegretol) and Tegretol (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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