Tegsedi and Cough - a phase IV clinical study of FDA data

Summary:

Cough is reported as a side effect among people who take Tegsedi (inotersen sodium), especially for people who are male, 60+ old, have been taking the drug for 2 - 5 years also take Aspirin, and have Hereditary neuropathic amyloidosis.

The phase IV clinical study analyzes which people have Cough when taking Tegsedi. It is created by eHealthMe based on reports of 2,040 people who have side effects when taking Tegsedi from the FDA, and is updated regularly.

What is Tegsedi?

Tegsedi has active ingredients of inotersen sodium. eHealthMe is studying from 2,040 Tegsedi users. Check the latest studies of Tegsedi.

What is Cough?

Cough is found to be associated with 3,047 drugs and 3,805 conditions by eHealthMe. Check the latest studies of Cough.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Jul, 13, 2026

2,040 people reported to have side effects when taking Tegsedi.
Among them, 53 people (2.6%) have Cough.

Among these 53 people:

How long have people been on Tegsedi when they have Cough? *

What is the gender of people who have Cough when taking Tegsedi? *

female: 45.16 %
male: 54.84 %

What is the age of people who have Cough when taking Tegsedi? *

What are other drugs people take besides Tegsedi? *

What are other side effects people have besides Cough? *

Fatigue (feeling of tiredness): 31 people, 58.49%
Malaise (a feeling of general discomfort or uneasiness): 27 people, 50.94%
Thrombocytopenia (decrease of platelets in blood): 24 people, 45.28%
Haemoglobin Decreased: 23 people, 43.40%
Protein Urine Present: 22 people, 41.51%
Urine Protein/creatinine Ratio Increased: 20 people, 37.74%
Blood Creatinine Increased: 20 people, 37.74%
Pain: 19 people, 35.85%
Weakness: 18 people, 33.96%
Dyspnea (difficult or laboured breathing): 18 people, 33.96%

What are the existing conditions these people have? *

Hereditary Neuropathic Amyloidosis (hereditary- diseases resulting from abnormal deposition of certain proteins (amyloid) in various bodily areas by problems with signals from the nerves): 47 people, 88.68%
Amyloidosis (a tumour within which amyloid is produced): 4 people, 7.55%
Fluid Retention (an abnormal accumulation of fluid in the blood): 2 people, 3.77%
Cardiomyopathy (weakening of the heart muscle): 2 people, 3.77%
Swelling: 2 people, 3.77%
Diarrhea: 2 people, 3.77%
Neuropathy Peripheral (surface nerve damage): 2 people, 3.77%
High Blood Pressure: 2 people, 3.77%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 2 people, 3.77%
Dry Eyes (lack of adequate tears): 1 person, 1.89%

* Approximation only. Some reports may have incomplete information.

Do you take Tegsedi and have Cough?

- Check whether Cough is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Tegsedi:

Tegsedi (2,040 reports)

Cough treatments and more:

Cough (361,792 reports)

Browse all side effects of Tegsedi:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Cough:

Cough (3,047 drugs)

Browse all the conditions that are associated with Cough:

Cough (3,805 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on inotersen sodium (the active ingredients of Tegsedi) and Tegsedi (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.