Tegsedi and Stroke - a phase IV clinical study of FDA data

Summary:

Stroke is reported as a side effect among people who take Tegsedi (inotersen sodium), especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months also take Metformin, and have Hereditary neuropathic amyloidosis.

The phase IV clinical study analyzes which people have Stroke when taking Tegsedi. It is created by eHealthMe based on reports of 2,040 people who have side effects when taking Tegsedi from the FDA, and is updated regularly.

What is Tegsedi?

Tegsedi has active ingredients of inotersen sodium. eHealthMe is studying from 2,040 Tegsedi users. Check the latest studies of Tegsedi.

What is Stroke?

Stroke (sudden death of a portion of the brain cells due to a lack of oxygen) is found to be associated with 2,335 drugs and 3,028 conditions by eHealthMe. Check the latest studies of Stroke.

On Jun, 21, 2026

2,040 people reported to have side effects when taking Tegsedi.
Among them, 29 people (1.42%) have Stroke.

Among these 29 people:

How long have people been on Tegsedi when they have Stroke? *

What is the gender of people who have Stroke when taking Tegsedi? *

female: 70.59 %
male: 29.41 %

What is the age of people who have Stroke when taking Tegsedi? *

What are other drugs people take besides Tegsedi? *

Metformin: 7 people, 24.14%
Aspirin: 5 people, 17.24%
Depakote: 5 people, 17.24%
Atorvastatin Calcium: 4 people, 13.79%
Baclofen: 4 people, 13.79%
Cyclobenzaprine Hydrochloride: 4 people, 13.79%
Eliquis: 4 people, 13.79%
Gabapentin: 4 people, 13.79%
Medroxyprogesterone Acetate: 4 people, 13.79%
Lasix: 3 people, 10.34%

What are other side effects people have besides Stroke? *

Hemiparesis (weakness on one side of the body): 7 people, 24.14%
Mental Disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability): 6 people, 20.69%
Oedema Peripheral (superficial swelling): 5 people, 17.24%
Protein Urine Present: 5 people, 17.24%
Weakness: 4 people, 13.79%
Speech Impairment (Adult) (inability to speak (adult)): 4 people, 13.79%
Injection Site Pain: 4 people, 13.79%
Influenza Like Illness: 4 people, 13.79%
Hypotension (abnormally low blood pressure): 4 people, 13.79%
Hemiplegia (paralysis of one side of the body): 4 people, 13.79%

What are the existing conditions these people have? *

Hereditary Neuropathic Amyloidosis (hereditary- diseases resulting from abnormal deposition of certain proteins (amyloid) in various bodily areas by problems with signals from the nerves): 28 people, 96.55%
Polyneuropathy (neurological disorder that occurs when many peripheral nerves throughout the body malfunction simultaneously): 1 person, 3.45%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 3.45%
Cardiac Failure: 1 person, 3.45%

* Approximation only. Some reports may have incomplete information.

Do you take Tegsedi and have Stroke?

- Check whether Stroke is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Tegsedi:

Tegsedi (2,040 reports)

Stroke treatments and more:

Stroke (334,635 reports)

Browse all side effects of Tegsedi:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Stroke:

Stroke (2,335 drugs)

Browse all the conditions that are associated with Stroke:

Stroke (3,028 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on inotersen sodium (the active ingredients of Tegsedi) and Tegsedi (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.