Temozolomide and Diplopia - a phase IV clinical study of FDA data

Summary:

Diplopia is reported as a side effect among people who take Temozolomide (temozolomide), especially for people who are male, 50-59 old, have been taking the drug for < 1 month also take Phenytoin, and have Brain neoplasm malignant.

The phase IV clinical study analyzes which people have Diplopia when taking Temozolomide. It is created by eHealthMe based on reports of 16,598 people who have side effects when taking Temozolomide from the FDA, and is updated regularly.

What is Temozolomide?

Temozolomide has active ingredients of temozolomide. It is often used in glioblastoma multiforme. eHealthMe is studying from 16,644 Temozolomide users. Check the latest studies of Temozolomide.

What is Diplopia?

Diplopia (double vision) is found to be associated with 1,429 drugs and 1,893 conditions by eHealthMe. Check the latest studies of Diplopia.



On Aug, 11, 2026

16,598 people reported to have side effects when taking Temozolomide.
Among them, 20 people (0.12%) have Diplopia.

Could Temozolomide cause Diplopia?

Among these 20 people:

How long have people been on Temozolomide when they have Diplopia? *

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Diplopia when taking Temozolomide? *

  • female: 20 %
  • male: 80 %

What is the age of people who have Diplopia when taking Temozolomide? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 7.14 %
  • 20-29: 0.0 %
  • 30-39: 28.57 %
  • 40-49: 7.14 %
  • 50-59: 42.86 %
  • 60+: 14.29 %

What are other drugs people take besides Temozolomide? *

  1. Phenytoin: 7 people, 35.00%
  2. Avastin: 5 people, 25.00%
  3. Keppra: 4 people, 20.00%
  4. Clonazepam: 4 people, 20.00%
  5. Decadron: 4 people, 20.00%
  6. Gemcitabine: 4 people, 20.00%
  7. Dexamethasone: 3 people, 15.00%
  8. Tarceva: 3 people, 15.00%
  9. Quetiapine Fumarate: 3 people, 15.00%
  10. Carmustine: 3 people, 15.00%

What are other side effects people have besides Diplopia? *

  1. Headache (pain in head): 10 people, 50.00%
  2. Haemorrhage (bleeding): 7 people, 35.00%
  3. Vision Blurred: 6 people, 30.00%
  4. Thrombocytopenia (decrease of platelets in blood): 6 people, 30.00%
  5. Fatigue (feeling of tiredness): 5 people, 25.00%
  6. Disease Progression: 5 people, 25.00%
  7. Cellulitis (infection under the skin): 4 people, 20.00%
  8. Depression: 4 people, 20.00%
  9. Cognitive Disorder (mental health disorders affects learning, memory, perception, and problem solving): 4 people, 20.00%
  10. Nausea And Vomiting: 4 people, 20.00%

What are the existing conditions these people have? *

  1. Brain Neoplasm Malignant (brain cancer tumour): 4 people, 20.00%
  2. Status Epilepticus (a life-threatening condition in which the brain is in a state of persistent seizure): 3 people, 15.00%
  3. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 2 people, 10.00%
  4. Pineal Parenchymal Neoplasm Malignant (pineal parenchymal cancerous tumour): 1 person, 5.00%
  5. Neoplasm Malignant (cancer tumour): 1 person, 5.00%
  6. Metastases To Bone (cancer spreads to bone): 1 person, 5.00%
  7. Anaplastic Astrocytoma (tumour of the glial (supportive) tissue of the brain): 1 person, 5.00%
  8. Acromegaly (body produces too much growth hormone, leading to excess growth of body tissues): 1 person, 5.00%

* Approximation only. Some reports may have incomplete information.

Do you take Temozolomide and have Diplopia?

- Check whether Diplopia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Temozolomide:

Diplopia treatments and more:

How severe was Diplopia and when was it recovered:

Expand to all the drugs that have ingredients of temozolomide:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Temozolomide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Diplopia:

Browse all the conditions that are associated with Diplopia:

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on temozolomide (the active ingredients of Temozolomide) and Temozolomide (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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