Tenormin and Hepatic necrosis - a phase IV clinical study of FDA data

Summary:

Hepatic necrosis is reported as a side effect among people who take Tenormin (atenolol), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Prednisone, and have Acute coronary syndrome.

The phase IV clinical study analyzes which people have Hepatic necrosis when taking Tenormin. It is created by eHealthMe based on reports of 20,083 people who have side effects when taking Tenormin from the FDA, and is updated regularly.

What is Tenormin?

Tenormin has active ingredients of atenolol. It is often used in high blood pressure. eHealthMe is studying from 20,474 Tenormin users. Check the latest studies of Tenormin.

What is Hepatic necrosis?

Hepatic necrosis (large portions of liver die off due to severe liver disease) is found to be associated with 588 drugs and 744 conditions by eHealthMe. Check the latest studies of Hepatic necrosis.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 01, 2026

20,083 people reported to have side effects when taking Tenormin.
Among them, 19 people (0.09%) have Hepatic necrosis.

Among these 19 people:

How long have people been on Tenormin when they have Hepatic necrosis? *

What is the gender of people who have Hepatic necrosis when taking Tenormin? *

female: 73.68 %
male: 26.32 %

What is the age of people who have Hepatic necrosis when taking Tenormin? *

What are other drugs people take besides Tenormin? *

What are other side effects people have besides Hepatic necrosis? *

Hepatic Failure (liver failure): 7 people, 36.84%
Autoimmune Hepatitis: 6 people, 31.58%
Pvt: 4 people, 21.05%
Gallstones (stone formation by bile component): 4 people, 21.05%
Hepatitis Fulminant (life-threatening condition defined by significantly impaired liver function): 4 people, 21.05%
Thrombocytopenia (decrease of platelets in blood): 3 people, 15.79%
Cholestasis (a condition where bile cannot flow from the liver to the duodenum): 3 people, 15.79%
Blood Urine Present: 3 people, 15.79%
Intestinal Ischaemia (decreased supply of oxygenated blood to the intestines): 3 people, 15.79%
Renal Tubular Necrosis (death of kidney tubules): 3 people, 15.79%

What are the existing conditions these people have? *

Acute Coronary Syndrome (acute chest pain and other symptoms that happen because the heart does not get blood): 2 people, 10.53%
Upper Respiratory Tract Infection: 1 person, 5.26%
Prostate Cancer: 1 person, 5.26%
Myocardial Ischaemia (the blood flow through one or more of the blood vessels that lead to heart (coronary arteries) is decreased): 1 person, 5.26%

* Approximation only. Some reports may have incomplete information.

Do you take Tenormin and have Hepatic necrosis?

- Check whether Hepatic necrosis is associated with a drug or a condition
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Tenormin:

Tenormin (20,474 reports)

Browse all side effects of Tenormin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hepatic necrosis:

Hepatic necrosis (588 drugs)

Browse all the conditions that are associated with Hepatic necrosis:

Hepatic necrosis (744 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on atenolol (the active ingredients of Tenormin) and Tenormin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.