Tessalon and Mitral valve incompetence - a phase IV clinical study of FDA data

Summary:

Mitral valve incompetence is reported as a side effect among people who take Tessalon (benzonatate), especially for people who are female, 60+ old, also take Digoxin, and have Pain.

The phase IV clinical study analyzes which people have Mitral valve incompetence when taking Tessalon. It is created by eHealthMe based on reports of 6,327 people who have side effects when taking Tessalon from the FDA, and is updated regularly.

What is Tessalon?

Tessalon has active ingredients of benzonatate. It is often used in cough. eHealthMe is studying from 6,493 Tessalon users. Check the latest studies of Tessalon.

What is Mitral valve incompetence?

Mitral valve incompetence (inefficient heart valve) is found to be associated with 1,433 drugs and 1,280 conditions by eHealthMe. Check the latest studies of Mitral valve incompetence.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 27, 2026

6,327 people reported to have side effects when taking Tessalon.
Among them, 37 people (0.58%) have Mitral valve incompetence.

Could Tessalon cause Mitral valve incompetence?

Among these 37 people:

What is the gender of people who have Mitral valve incompetence when taking Tessalon? *

female: 58.33 %
male: 41.67 %

What is the age of people who have Mitral valve incompetence when taking Tessalon? *

What are other drugs people take besides Tessalon? *

What are other side effects people have besides Mitral valve incompetence? *

Tricuspid Valve Incompetence (inefficient heart valve): 23 people, 62.16%
Stress And Anxiety: 19 people, 51.35%
Dyspnea (difficult or laboured breathing): 18 people, 48.65%
Weakness: 17 people, 45.95%
Cardiac Failure Congestive: 17 people, 45.95%
Injury: 16 people, 43.24%
Fatigue (feeling of tiredness): 16 people, 43.24%
Dizziness: 15 people, 40.54%
Pleural Effusion (water on the lungs): 15 people, 40.54%
Chest Pain: 14 people, 37.84%

What are the existing conditions these people have? *

Idiopathic Pulmonary Fibrosis (chronic lung disease): 4 people, 10.81%
Pain: 4 people, 10.81%
Sleep Disorder: 3 people, 8.11%
Lung Cancer - Non-Small Cell (lung cancer): 3 people, 8.11%
Nausea (feeling of having an urge to vomit): 2 people, 5.41%
Cardiac Failure Congestive: 2 people, 5.41%
Herpes Virus Infection: 2 people, 5.41%
Hypertensive Heart Disease: 2 people, 5.41%
Insomnia (sleeplessness): 2 people, 5.41%
Muscle Aches (muscle pain): 2 people, 5.41%

* Approximation only. Some reports may have incomplete information.

Do you take Tessalon and have Mitral valve incompetence?

- Check whether Mitral valve incompetence is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Tessalon:

Tessalon (6,493 reports)

Browse all side effects of Tessalon:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Mitral valve incompetence:

Mitral valve incompetence (1,433 drugs)

Browse all the conditions that are associated with Mitral valve incompetence:

Mitral valve incompetence (1,280 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on benzonatate (the active ingredients of Tessalon) and Tessalon (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.