Theo-dur and Intestinal obstruction - a phase IV clinical study of FDA data

Summary:

Intestinal obstruction is reported as a side effect among people who take Theo-dur (theophylline), especially for people who are male, 60+ old, have been taking the drug for 2 - 5 years also take Spiriva, and have High blood pressure.

The phase IV clinical study analyzes which people have Intestinal obstruction when taking Theo-dur. It is created by eHealthMe based on reports of 4,432 people who have side effects when taking Theo-dur from the FDA, and is updated regularly.

What is Theo-dur?

Theo-dur has active ingredients of theophylline. It is often used in asthma. eHealthMe is studying from 4,451 Theo-dur users. Check the latest studies of Theo-dur.

What is Intestinal obstruction?

Intestinal obstruction is found to be associated with 1,887 drugs and 2,613 conditions by eHealthMe. Check the latest studies of Intestinal obstruction.

On Jul, 09, 2026

4,432 people reported to have side effects when taking Theo-dur.
Among them, 38 people (0.86%) have Intestinal obstruction.

Could Theo-dur cause Intestinal obstruction?

Among these 38 people:

How long have people been on Theo-dur when they have Intestinal obstruction? *

What is the gender of people who have Intestinal obstruction when taking Theo-dur? *

female: 32.43 %
male: 67.57 %

What is the age of people who have Intestinal obstruction when taking Theo-dur? *

What are other drugs people take besides Theo-dur? *

What are other side effects people have besides Intestinal obstruction? *

Constipation: 14 people, 36.84%
Pneumonia: 11 people, 28.95%
Sepsis (a severe blood infection that can lead to organ failure and death): 11 people, 28.95%
Acute Kidney Failure: 9 people, 23.68%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 9 people, 23.68%
Abdominal Pain: 8 people, 21.05%
Nausea And Vomiting: 8 people, 21.05%
Nausea (feeling of having an urge to vomit): 8 people, 21.05%
Dyspnea (difficult or laboured breathing): 8 people, 21.05%
Gastric Ulcer (stomach ulcer): 7 people, 18.42%

What are the existing conditions these people have? *

High Blood Pressure: 6 people, 15.79%
Multiple Myeloma (cancer of the plasma cells): 5 people, 13.16%
Cardiac Asthma (wheezing, coughing or shortness of breath due to congestive heart failure): 4 people, 10.53%
Insomnia (sleeplessness): 4 people, 10.53%
Arrhythmias (irregular heartbeat): 4 people, 10.53%
Bone Loss: 4 people, 10.53%
Chronic Respiratory Failure: 4 people, 10.53%
Emphysema (chronic respiratory disease - over inflation of the air sacs (alveoli) in the lungs): 3 people, 7.89%
Rectal Cancer Metastatic (cancer of rectum spreads to other): 2 people, 5.26%
Bronchiectasis (abnormal widening of the bronchi or their branches, causing a risk of infection): 2 people, 5.26%

* Approximation only. Some reports may have incomplete information.

Do you take Theo-dur and have Intestinal obstruction?

- Check whether Intestinal obstruction is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Theo-dur:

Theo-dur (4,451 reports)

Browse all side effects of Theo-dur:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Intestinal obstruction:

Intestinal obstruction (1,887 drugs)

Browse all the conditions that are associated with Intestinal obstruction:

Intestinal obstruction (2,613 conditions)

Related publications that referenced our studies

Korang-Yeboah M, Rahman Z, Shah D, Mohammad A, Wu S, Siddiqui A, Khan MA, "Impact of formulation and process variables on solid-state stability of theophylline in controlled release formulations", International journal of pharmaceutics, 2016 Feb .
Dhaval MK, "Impact of formulation and process variables on solid-state stability of theophylline in controlled release formulations", International Journal of Pharmaceutics, 2016 Jan .
Korang-Yeboah M, Rahman Z, Shah D, Mohammad A, Wu S, Siddiqui A, Khan MA, "Impact of formulation and process variables on solid-state stability of theophylline in controlled release formulations", International journal of pharmaceutics, 2016 Feb .
Dhaval MK, "Impact of formulation and process variables on solid-state stability of theophylline in controlled release formulations", International Journal of Pharmaceutics, 2016 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on theophylline (the active ingredients of Theo-dur) and Theo-dur (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.