Theophyl and Oa - a phase IV clinical study of FDA data

Summary:

Oa is reported as a side effect among people who take Theophyl (theophylline), especially for people who are female, 60+ old, have been taking the drug for 1 - 2 years also take Albuterol, and have Asthma.

The phase IV clinical study analyzes which people have Oa when taking Theophyl. It is created by eHealthMe based on reports of 18,974 people who have side effects when taking Theophyl from the FDA, and is updated regularly.

What is Theophyl?

Theophyl has active ingredients of theophylline. eHealthMe is studying from 19,174 Theophyl users. Check the latest studies of Theophyl.

What is Oa?

Oa (osteoarthritis /a joint disease caused by cartilage loss in a joint) is found to be associated with 1,887 drugs and 2,643 conditions by eHealthMe. Check the latest studies of Oa.

On May, 01, 2026

18,974 people reported to have side effects when taking Theophyl.
Among them, 78 people (0.41%) have Oa.

Among these 78 people:

How long have people been on Theophyl when they have Oa? *

What is the gender of people who have Oa when taking Theophyl? *

female: 64.86 %
male: 35.14 %

What is the age of people who have Oa when taking Theophyl? *

What are other drugs people take besides Theophyl? *

What are other side effects people have besides Oa? *

Stress And Anxiety: 36 people, 46.15%
Weight Decreased: 31 people, 39.74%
High Blood Pressure: 27 people, 34.62%
Pain: 27 people, 34.62%
Dyspnea (difficult or laboured breathing): 25 people, 32.05%
Fall: 25 people, 32.05%
Fatigue (feeling of tiredness): 24 people, 30.77%
Back Pain: 23 people, 29.49%
Rib Fracture: 22 people, 28.21%
Joint Pain: 21 people, 26.92%

What are the existing conditions these people have? *

Asthma: 28 people, 35.90%
Osteoporosis (bones weak and more likely to break): 18 people, 23.08%
Pain: 10 people, 12.82%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 8 people, 10.26%
High Blood Cholesterol: 7 people, 8.97%
Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 7 people, 8.97%
Muscle Spasms (muscle contraction): 6 people, 7.69%
Fluid Retention (an abnormal accumulation of fluid in the blood): 5 people, 6.41%
Depression: 5 people, 6.41%
High Blood Pressure: 5 people, 6.41%

* Approximation only. Some reports may have incomplete information.

Do you take Theophyl and have Oa?

- Check whether Oa is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Theophyl:

Theophyl (19,174 reports)

Oa treatments and more:

Oa (95,654 reports)

Browse all side effects of Theophyl:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Oa:

Oa (1,887 drugs)

Browse all the conditions that are associated with Oa:

Oa (2,643 conditions)

Related publications that referenced our studies

Korang-Yeboah M, Rahman Z, Shah D, Mohammad A, Wu S, Siddiqui A, Khan MA, "Impact of formulation and process variables on solid-state stability of theophylline in controlled release formulations", International journal of pharmaceutics, 2016 Feb .
Dhaval MK, "Impact of formulation and process variables on solid-state stability of theophylline in controlled release formulations", International Journal of Pharmaceutics, 2016 Jan .
Korang-Yeboah M, Rahman Z, Shah D, Mohammad A, Wu S, Siddiqui A, Khan MA, "Impact of formulation and process variables on solid-state stability of theophylline in controlled release formulations", International journal of pharmaceutics, 2016 Feb .
Dhaval MK, "Impact of formulation and process variables on solid-state stability of theophylline in controlled release formulations", International Journal of Pharmaceutics, 2016 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on theophylline (the active ingredients of Theophyl) and Theophyl (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.