Ticlid and Hyperpyrexia - a phase IV clinical study of FDA data
Summary:
Hyperpyrexia is reported as a side effect among people who take Ticlid (ticlopidine hydrochloride), especially for people who are male, 60+ old, have been taking the drug for 1 - 2 years also take Digoxin, and have Schizophrenia.
The phase IV clinical study analyzes which people have Hyperpyrexia when taking Ticlid. It is created by eHealthMe based on reports of 3,085 people who have side effects when taking Ticlid from the FDA, and is updated regularly.
What is Ticlid?
Ticlid has active ingredients of ticlopidine hydrochloride. eHealthMe is studying from 3,094 Ticlid users. Check the latest studies of Ticlid.
What is Hyperpyrexia?
Hyperpyrexia (extremely high fever) is found to be associated with 367 drugs and 530 conditions by eHealthMe. Check the latest studies of Hyperpyrexia.
eHealthMe: drug outcomes in the real world
eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.
3,085 people reported to have side effects when taking Ticlid.
Among them, 13 people (0.42%) have Hyperpyrexia.

Among these 13 people:
How long have people been on Ticlid when they have Hyperpyrexia? *
- < 1 month: 0.0 %
- 1 - 6 months: 0.0 %
- 6 - 12 months: 0.0 %
- 1 - 2 years: 100 %
- 2 - 5 years: 0.0 %
- 5 - 10 years: 0.0 %
- 10+ years: 0.0 %
What is the gender of people who have Hyperpyrexia when taking Ticlid? *
- female: 46.15 %
- male: 53.85 %
What is the age of people who have Hyperpyrexia when taking Ticlid? *
- 0-1: 0.0 %
- 2-9: 0.0 %
- 10-19: 0.0 %
- 20-29: 0.0 %
- 30-39: 0.0 %
- 40-49: 0.0 %
- 50-59: 25 %
- 60+: 75 %
What are other drugs people take besides Ticlid? *
- Digoxin: 3 people, 23.08%
- Indomethacin: 2 people, 15.38%
- Flurbiprofen: 2 people, 15.38%
- Olanzapine: 2 people, 15.38%
- Diazepam: 2 people, 15.38%
- Lopressor: 2 people, 15.38%
- Lisinopril: 2 people, 15.38%
- Diclofenac Sodium: 2 people, 15.38%
- Flavoxate Hydrochloride: 2 people, 15.38%
- Furosemide: 2 people, 15.38%
What are other side effects people have besides Hyperpyrexia? *
- Weakness: 4 people, 30.77%
- Dehydration (dryness resulting from the removal of water): 3 people, 23.08%
- Confusion: 3 people, 23.08%
- Thrombocytopenia (decrease of platelets in blood): 3 people, 23.08%
- Tachypnea: 3 people, 23.08%
- Chills (felling of cold): 2 people, 15.38%
- Cardiac Failure Aggravated: 2 people, 15.38%
- Blood Lactate Dehydrogenase Increased: 2 people, 15.38%
- Hyperuricaemia (level of uric acid in the blood that is abnormally high): 2 people, 15.38%
- Blood Creatinine Increased: 2 people, 15.38%
What are the existing conditions these people have? *
- Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 2 people, 15.38%
* Approximation only. Some reports may have incomplete information.
Do you take Ticlid and have Hyperpyrexia?
- Check whether Hyperpyrexia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, long term effects of, and alternative drugs to Ticlid:
- Ticlid (3,094 reports)
Hyperpyrexia treatments and more:
- Hyperpyrexia (4,941 reports)
How severe was Hyperpyrexia and when was it recovered:
Expand to all the drugs that have ingredients of ticlopidine hydrochloride:
Sub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Ticlid:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all the drugs that are associated with Hyperpyrexia:
- Hyperpyrexia (367 drugs)
Browse all the conditions that are associated with Hyperpyrexia:
- Hyperpyrexia (530 conditions)
Related publications that referenced our studies
- Jacob S, Dunn BL, Qureshi ZP, Bandarenko N, Kwaan HC, Pandey DK, McKoy JM, Barnato SE, Winters JL, Cursio JF, Weiss I, "Ticlopidine-, clopidogrel-, and prasugrel-associated thrombotic thrombocytopenic purpura: a 20-year review from the Southern Network on Adverse Reactions (SONAR)", InSeminars in thrombosis and hemostasis, 2012 Jan .
- Frank P, "Ticlopidine-, Clopidogrel-, and Prasugrel-Associated Thrombotic Thrombocytopenic Purpura: A Twenty-Year Review from the Southern Network on Adverse Reactions (SONAR)", , 2012 Jan .
- Jacob S, Dunn BL, Qureshi ZP, Bandarenko N, Kwaan HC, Pandey DK, McKoy JM, Barnato SE, Winters JL, Cursio JF, Weiss I, "Ticlopidine-, clopidogrel-, and prasugrel-associated thrombotic thrombocytopenic purpura: a 20-year review from the Southern Network on Adverse Reactions (SONAR)", InSeminars in thrombosis and hemostasis, 2012 Jan .
- Frank P, "Ticlopidine-, Clopidogrel-, and Prasugrel-Associated Thrombotic Thrombocytopenic Purpura: A Twenty-Year Review from the Southern Network on Adverse Reactions (SONAR)", , 2012 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on ticlopidine hydrochloride (the active ingredients of Ticlid) and Ticlid (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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