Tigan and Acute kidney failure - a phase IV clinical study of FDA data

Summary:

Acute kidney failure is reported as a side effect among people who take Tigan (trimethobenzamide hydrochloride), especially for people who are male, 50-59 old, also take Nexium, and have Gastroesophageal reflux disease.

The phase IV clinical study analyzes which people have Acute kidney failure when taking Tigan. It is created by eHealthMe based on reports of 1,873 people who have side effects when taking Tigan from the FDA, and is updated regularly.

What is Tigan?

Tigan has active ingredients of trimethobenzamide hydrochloride. It is often used in nausea. eHealthMe is studying from 1,904 Tigan users. Check the latest studies of Tigan.

What is Acute kidney failure?

Acute kidney failure is found to be associated with 2,836 drugs and 4,492 conditions by eHealthMe. Check the latest studies of Acute kidney failure.

On Jul, 20, 2026

1,873 people reported to have side effects when taking Tigan.
Among them, 31 people (1.66%) have Acute kidney failure.

Among these 31 people:

What is the gender of people who have Acute kidney failure when taking Tigan? *

female: 41.94 %
male: 58.06 %

What is the age of people who have Acute kidney failure when taking Tigan? *

What are other drugs people take besides Tigan? *

What are other side effects people have besides Acute kidney failure? *

Pneumonia: 13 people, 41.94%
Arrhythmias (irregular heartbeat): 10 people, 32.26%
Hepatic Failure (liver failure): 10 people, 32.26%
Septic Shock (shock due to blood infection): 10 people, 32.26%
Cardiac Failure Congestive: 10 people, 32.26%
Liver Disorder (liver diseases): 9 people, 29.03%
Haemolysis (breaking open of red blood cells and the release of haemoglobin into the surrounding fluid): 9 people, 29.03%
Azotaemia (excess of urea or other nitrogenous compounds in the blood): 9 people, 29.03%
Gastrointestinal Haemorrhage (bleeding gastrointestinal tract): 9 people, 29.03%
Cerebellar Ischaemia (lack of blood supply to cerebeller): 9 people, 29.03%

What are the existing conditions these people have? *

Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 7 people, 22.58%
Pain: 5 people, 16.13%
High Blood Pressure: 4 people, 12.90%
Sleep Disorder: 3 people, 9.68%
Diabetes: 2 people, 6.45%
Gastric Ph Decreased: 2 people, 6.45%
Gout (uric acid crystals building up in the body): 2 people, 6.45%
Impaired Gastric Emptying: 2 people, 6.45%
Hepatitis C: 1 person, 3.23%
Heart Attack: 1 person, 3.23%

* Approximation only. Some reports may have incomplete information.

Do you take Tigan and have Acute kidney failure?

- Check whether Acute kidney failure is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Tigan:

Tigan (1,904 reports)

Acute kidney failure treatments and more:

Acute kidney failure (259,717 reports)

How severe was Acute kidney failure and when was it recovered:

Acute kidney failure in Tigan

Expand to all the drugs that have ingredients of trimethobenzamide hydrochloride:

Acute kidney failure and drugs with ingredients of trimethobenzamide hydrochloride

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Tigan:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Acute kidney failure:

Acute kidney failure (2,836 drugs)

Browse all the conditions that are associated with Acute kidney failure:

Acute kidney failure (4,492 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on trimethobenzamide hydrochloride (the active ingredients of Tigan) and Tigan (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.