Tigan and Anaphylaxis - a phase IV clinical study of FDA data

Summary:

Anaphylaxis is reported as a side effect among people who take Tigan (trimethobenzamide hydrochloride), especially for people who are female, 50-59 old, also take Compazine, and have Abdominal discomfort.

The phase IV clinical study analyzes which people have Anaphylaxis when taking Tigan. It is created by eHealthMe based on reports of 1,873 people who have side effects when taking Tigan from the FDA, and is updated regularly.

What is Tigan?

Tigan has active ingredients of trimethobenzamide hydrochloride. It is often used in nausea. eHealthMe is studying from 1,904 Tigan users. Check the latest studies of Tigan.

What is Anaphylaxis?

Anaphylaxis (serious allergic reaction that is rapid in onset and may cause death) is found to be associated with 1,942 drugs and 2,855 conditions by eHealthMe. Check the latest studies of Anaphylaxis.

On Jul, 07, 2026

1,873 people reported to have side effects when taking Tigan.
Among them, 15 people (0.8%) have Anaphylaxis.

Among these 15 people:

What is the gender of people who have Anaphylaxis when taking Tigan? *

female: 100 %
male: 0.0 %

What is the age of people who have Anaphylaxis when taking Tigan? *

What are other drugs people take besides Tigan? *

Compazine: 9 people, 60.00%
Zofran: 8 people, 53.33%
Phenergan: 5 people, 33.33%
Demerol: 5 people, 33.33%
Wygesic: 5 people, 33.33%
Vistaril: 5 people, 33.33%
Codeine: 5 people, 33.33%
Reglan: 5 people, 33.33%
Pseudoephedrine Hydrochloride: 4 people, 26.67%
Alprazolam: 4 people, 26.67%

What are other side effects people have besides Anaphylaxis? *

Hypoaesthesia (reduced sense of touch or sensation): 4 people, 26.67%
Nervousness: 4 people, 26.67%
Benign Breast Neoplasm (benign (non-cancerous) tumours of the breast): 4 people, 26.67%
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 4 people, 26.67%
Joint Range Of Motion Decreased (disease of joint movement): 4 people, 26.67%
Arthropathy: 4 people, 26.67%
Tremor (trembling or shaking movements in one or more parts of your body): 4 people, 26.67%
Fluid Retention (an abnormal accumulation of fluid in the blood): 3 people, 20.00%
Drug Hypersensitivity: 3 people, 20.00%
Obsessive-Compulsive Disorder (an anxiety disorder characterized by intrusive thoughts that produce uneasiness, apprehension, fear, or worry;): 3 people, 20.00%

What are the existing conditions these people have? *

Stress And Anxiety: 4 people, 26.67%
Panic Disorder: 4 people, 26.67%
Obsessive-Compulsive Disorder (an anxiety disorder characterized by intrusive thoughts that produce uneasiness, apprehension, fear, or worry;): 4 people, 26.67%
Nausea And Vomiting: 4 people, 26.67%
Abdominal Discomfort: 4 people, 26.67%
Ovarian Adenocarcinoma (cancer tumour of ovary): 3 people, 20.00%
Osteoporosis (bones weak and more likely to break): 1 person, 6.67%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 6.67%
Angioedema (rapid swelling of the dermis): 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

Do you take Tigan and have Anaphylaxis?

- Check whether Anaphylaxis is associated with a drug or a condition
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Tigan:

Tigan (1,904 reports)

Anaphylaxis treatments and more:

Anaphylaxis (91,195 reports)

How severe was Anaphylaxis and when was it recovered:

Anaphylaxis in Tigan

Expand to all the drugs that have ingredients of trimethobenzamide hydrochloride:

Anaphylaxis and drugs with ingredients of trimethobenzamide hydrochloride (16 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Tigan:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Anaphylaxis:

Anaphylaxis (1,942 drugs)

Browse all the conditions that are associated with Anaphylaxis:

Anaphylaxis (2,855 conditions)

Related publications that referenced our studies

An?eli? N, Erdeljan S, Popovi? R, Bo?i? T, "Anaphylaxis on graft reperfusion during orthotopic liver transplantation: A case study", Srpski arhiv za celokupno lekarstvo, 2016 Jan .
Thangakunam B, Christopher DJ, Mathews V, Srivastava A, "Mesenchymal stromal stem cell therapy in advanced interstitial lung disease-Anaphylaxis and short-term follow-up", Lung India: official organ of Indian Chest Society, 2015 Jan .
Guensley Delva, M. D., & Muse, I, "Rare case of laryngeal edema and anaphylaxis to Ofirmev (IV Acetaminophen): Case Report", , 2012 Jan .
Azkur D, Yoldas T, Toyran M, Kocabas CN, "A pediatric case of anaphylaxis due to octreotide", Asian Pacific journal of allergy and immunology, 2011 Dec .
An?eli? N, Erdeljan S, Popovi? R, Bo?i? T, "Anaphylaxis on graft reperfusion during orthotopic liver transplantation: A case study", Srpski arhiv za celokupno lekarstvo, 2016 Jan .
Thangakunam B, Christopher DJ, Mathews V, Srivastava A, "Mesenchymal stromal stem cell therapy in advanced interstitial lung disease-Anaphylaxis and short-term follow-up", Lung India: official organ of Indian Chest Society, 2015 Jan .
Guensley Delva, M. D., & Muse, I, "Rare case of laryngeal edema and anaphylaxis to Ofirmev (IV Acetaminophen): Case Report", , 2012 Jan .
Azkur D, Yoldas T, Toyran M, Kocabas CN, "A pediatric case of anaphylaxis due to octreotide", Asian Pacific journal of allergy and immunology, 2011 Dec .

How the study uses the data?

The study uses data from the FDA. It is based on trimethobenzamide hydrochloride (the active ingredients of Tigan) and Tigan (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.