Tigan and Intestinal obstruction - a phase IV clinical study of FDA data

Summary:

Intestinal obstruction is reported as a side effect among people who take Tigan (trimethobenzamide hydrochloride), especially for people who are female, 20-29 old, have been taking the drug for < 1 month also take Compazine, and have Dehydration.

The phase IV clinical study analyzes which people have Intestinal obstruction when taking Tigan. It is created by eHealthMe based on reports of 1,873 people who have side effects when taking Tigan from the FDA, and is updated regularly.

What is Tigan?

Tigan has active ingredients of trimethobenzamide hydrochloride. It is often used in nausea. eHealthMe is studying from 1,904 Tigan users. Check the latest studies of Tigan.

What is Intestinal obstruction?

Intestinal obstruction is found to be associated with 1,887 drugs and 2,613 conditions by eHealthMe. Check the latest studies of Intestinal obstruction.

On Jul, 13, 2026

1,873 people reported to have side effects when taking Tigan.
Among them, 11 people (0.59%) have Intestinal obstruction.

Could Tigan cause Intestinal obstruction?

Among these 11 people:

How long have people been on Tigan when they have Intestinal obstruction? *

What is the gender of people who have Intestinal obstruction when taking Tigan? *

female: 54.55 %
male: 45.45 %

What is the age of people who have Intestinal obstruction when taking Tigan? *

What are other drugs people take besides Tigan? *

What are other side effects people have besides Intestinal obstruction? *

Kidney Stones: 9 people, 81.82%
Rectal Haemorrhage (bleeding from anus): 9 people, 81.82%
White Blood Cell Count Increased: 6 people, 54.55%
Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall): 6 people, 54.55%
High Blood Cholesterol: 6 people, 54.55%
Gastroenteritis (inflammation of stomach and intestine): 6 people, 54.55%
Gastritis (inflammation of stomach): 6 people, 54.55%
Epstein-Barr Virus Infection: 6 people, 54.55%
Diarrhea: 6 people, 54.55%
Inflammatory Bowel Disease: 6 people, 54.55%

What are the existing conditions these people have? *

Sleep Disorder: 3 people, 27.27%
Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 3 people, 27.27%
Pulmonary Embolism (blockage of the main artery of the lung): 3 people, 27.27%
Pneumonia Aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree): 3 people, 27.27%
Pain: 3 people, 27.27%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 3 people, 27.27%
Hypotension (abnormally low blood pressure): 3 people, 27.27%
Dehydration (dryness resulting from the removal of water): 3 people, 27.27%

* Approximation only. Some reports may have incomplete information.

Do you take Tigan and have Intestinal obstruction?

- Check whether Intestinal obstruction is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Tigan:

Tigan (1,904 reports)

Intestinal obstruction treatments and more:

Intestinal obstruction (59,346 reports)

How severe was Intestinal obstruction and when was it recovered:

Intestinal obstruction in Tigan

Expand to all the drugs that have ingredients of trimethobenzamide hydrochloride:

Intestinal obstruction and drugs with ingredients of trimethobenzamide hydrochloride (11 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Tigan:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Intestinal obstruction:

Intestinal obstruction (1,887 drugs)

Browse all the conditions that are associated with Intestinal obstruction:

Intestinal obstruction (2,613 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on trimethobenzamide hydrochloride (the active ingredients of Tigan) and Tigan (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.