Tikosyn and Insomnia exacerbated - a phase IV clinical study of FDA data
Summary:
Insomnia exacerbated is reported as a side effect among people who take Tikosyn (dofetilide), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Coumadin, and have High blood pressure.
The phase IV clinical study analyzes which people have Insomnia exacerbated when taking Tikosyn. It is created by eHealthMe based on reports of 11,814 people who have side effects when taking Tikosyn from the FDA, and is updated regularly.
What is Tikosyn?
Tikosyn has active ingredients of dofetilide. It is often used in atrial fibrillation/flutter. eHealthMe is studying from 12,202 Tikosyn users. Check the latest studies of Tikosyn.
What is Insomnia exacerbated?
Insomnia exacerbated (severe sleeplessness) is found to be associated with 2,690 drugs and 976 conditions by eHealthMe. Check the latest studies of Insomnia exacerbated.
eHealthMe: drug outcomes in the real world
eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.
11,814 people reported to have side effects when taking Tikosyn.
Among them, 225 people (1.9%) have Insomnia exacerbated.

Among these 225 people:
How long have people been on Tikosyn when they have Insomnia exacerbated? *
What is the gender of people who have Insomnia exacerbated when taking Tikosyn? *
What is the age of people who have Insomnia exacerbated when taking Tikosyn? *
What are other drugs people take besides Tikosyn? *
What are other side effects people have besides Insomnia exacerbated? *
What are the existing conditions these people have? *
* Approximation only. Some reports may have incomplete information.
Do you take Tikosyn and have Insomnia exacerbated?
- Check whether Insomnia exacerbated is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, long term effects of, and alternative drugs to Tikosyn:
- Tikosyn (12,202 reports)
Insomnia exacerbated treatments and more:
- Insomnia exacerbated (337 reports)
How severe was Insomnia exacerbated and when was it recovered:
Expand to all the drugs that have ingredients of dofetilide:
Sub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Tikosyn:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all the drugs that are associated with Insomnia exacerbated:
- Insomnia exacerbated (2,690 drugs)
Browse all the conditions that are associated with Insomnia exacerbated:
- Insomnia exacerbated (976 conditions)
How the study uses the data?
The study uses data from the FDA. It is based on dofetilide (the active ingredients of Tikosyn) and Tikosyn (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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