Tikosyn and Skin blushing/flushing - a phase IV clinical study of FDA data

Summary:

Skin blushing/flushing is reported as a side effect among people who take Tikosyn (dofetilide), especially for people who are male, 60+ old, have been taking the drug for 6 - 12 months also take Niaspan, and have High blood pressure.

The phase IV clinical study analyzes which people have Skin blushing/flushing when taking Tikosyn. It is created by eHealthMe based on reports of 11,814 people who have side effects when taking Tikosyn from the FDA, and is updated regularly.

What is Tikosyn?

Tikosyn has active ingredients of dofetilide. It is often used in atrial fibrillation/flutter. eHealthMe is studying from 12,202 Tikosyn users. Check the latest studies of Tikosyn.

What is Skin blushing/flushing?

Skin blushing/flushing (a sudden reddening of the face, neck) is found to be associated with 2,012 drugs and 2,934 conditions by eHealthMe. Check the latest studies of Skin blushing/flushing.

On Aug, 09, 2026

11,814 people reported to have side effects when taking Tikosyn.
Among them, 49 people (0.41%) have Skin blushing/flushing.

Could Tikosyn cause Skin blushing/flushing?

Among these 49 people:

How long have people been on Tikosyn when they have Skin blushing/flushing? *

What is the gender of people who have Skin blushing/flushing when taking Tikosyn? *

female: 40.43 %
male: 59.57 %

What is the age of people who have Skin blushing/flushing when taking Tikosyn? *

What are other drugs people take besides Tikosyn? *

What are other side effects people have besides Skin blushing/flushing? *

Fatigue (feeling of tiredness): 13 people, 26.53%
Headache (pain in head): 13 people, 26.53%
Dizziness: 11 people, 22.45%
Dyspnea (difficult or laboured breathing): 11 people, 22.45%
Diarrhea: 10 people, 20.41%
Hypotension (abnormally low blood pressure): 10 people, 20.41%
Heart Palpitations (feelings or sensations that your heart is pounding or racing): 7 people, 14.29%
Weakness: 7 people, 14.29%
Chest Pain: 6 people, 12.24%
Drug Ineffective: 5 people, 10.20%

What are the existing conditions these people have? *

High Blood Cholesterol: 5 people, 10.20%
High Blood Pressure: 5 people, 10.20%
Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 4 people, 8.16%
Coronary Heart Disease (narrowing or blockage of the coronary arteries): 3 people, 6.12%
Depression: 3 people, 6.12%
Atrial Tachycardia (rhythm disturbance that arises in the atria): 2 people, 4.08%
Pain: 2 people, 4.08%
Cardiac Disorder: 2 people, 4.08%
Corneal Oedema (corneal swelling): 2 people, 4.08%
Hyperlipidaemia (presence of excess lipids in the blood): 2 people, 4.08%

* Approximation only. Some reports may have incomplete information.

Do you take Tikosyn and have Skin blushing/flushing?

- Check whether Skin blushing/flushing is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Tikosyn:

Tikosyn (12,202 reports)

Browse all side effects of Tikosyn:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Skin blushing/flushing:

Skin blushing/flushing (2,012 drugs)

Browse all the conditions that are associated with Skin blushing/flushing:

Skin blushing/flushing (2,934 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on dofetilide (the active ingredients of Tikosyn) and Tikosyn (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.