Tobi podhaler and Drug level increased - a phase IV clinical study of FDA data

Summary:

Drug level increased is reported as a side effect among people who take Tobi podhaler (tobramycin), especially for people who are male, 10-19 old, have been taking the drug for 6 - 12 months also take Melatonin, and have Gastroesophageal reflux disease.

The phase IV clinical study analyzes which people have Drug level increased when taking Tobi podhaler. It is created by eHealthMe based on reports of 3,403 people who have side effects when taking Tobi podhaler from the FDA, and is updated regularly.

What is Tobi podhaler?

Tobi podhaler has active ingredients of tobramycin. eHealthMe is studying from 3,406 Tobi podhaler users. Check the latest studies of Tobi podhaler.

What is Drug level increased?

Drug level increased is found to be associated with 875 drugs and 1,136 conditions by eHealthMe. Check the latest studies of Drug level increased.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Aug, 28, 2026

3,403 people reported to have side effects when taking Tobi podhaler.
Among them, 12 people (0.35%) have Drug level increased.

Could Tobi podhaler cause Drug level increased?

Among these 12 people:

How long have people been on Tobi podhaler when they have Drug level increased? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 50 %
  • 6 - 12 months: 50 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Drug level increased when taking Tobi podhaler? *

  • female: 25 %
  • male: 75 %

What is the age of people who have Drug level increased when taking Tobi podhaler? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 70 %
  • 20-29: 10 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 10 %
  • 60+: 10 %

What are other drugs people take besides Tobi podhaler? *

  1. Pulmozyme: 7 people, 58.33%
  2. Creon: 7 people, 58.33%
  3. Melatonin: 7 people, 58.33%
  4. Zantac: 6 people, 50.00%
  5. Cayston: 6 people, 50.00%
  6. Heparin: 6 people, 50.00%
  7. Intuniv: 6 people, 50.00%
  8. Latuda: 6 people, 50.00%
  9. Escitalopram: 5 people, 41.67%
  10. Focalin Xr: 4 people, 33.33%

What are other side effects people have besides Drug level increased? *

  1. Infective Pulmonary Exacerbation Of Cystic Fibrosis (severe infective lung disease with production of abnormally thick mucus): 7 people, 58.33%
  2. Sinusitis (inflammation of sinus): 6 people, 50.00%
  3. Alanine Aminotransferase Increased: 6 people, 50.00%
  4. Blood Alkaline Phosphatase Increased: 6 people, 50.00%
  5. Blood Creatinine Decreased: 6 people, 50.00%
  6. Blood Urea Increased: 6 people, 50.00%
  7. Carbon Dioxide Increased: 6 people, 50.00%
  8. Dyspnea (difficult or laboured breathing): 6 people, 50.00%
  9. Red Blood Cell Count Increased: 6 people, 50.00%
  10. White Blood Cell Count Increased: 6 people, 50.00%

What are the existing conditions these people have? *

  1. Sleep Disorder: 6 people, 50.00%
  2. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 6 people, 50.00%
  3. Sinus Congestion (blockage of sinus): 5 people, 41.67%
  4. Attention Deficit Hyperactivity Disorder (a chronic condition including attention difficulty, hyperactivity, and impulsiveness): 5 people, 41.67%
  5. Bipolar Disorder (mood disorder): 5 people, 41.67%
  6. Pain: 5 people, 41.67%
  7. Infective Pulmonary Exacerbation Of Cystic Fibrosis (severe infective lung disease with production of abnormally thick mucus): 5 people, 41.67%
  8. Wheezing (a high-pitched whistling sound made while you breath): 4 people, 33.33%
  9. Pseudomonas Infection (pseudomonas infection is caused by a bacterium, pseudomonas aeruginosa): 4 people, 33.33%
  10. Jock Itch (fungal infection of the groin and upper thighs): 4 people, 33.33%

* Approximation only. Some reports may have incomplete information.

Do you take Tobi podhaler and have Drug level increased?

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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Tobi podhaler:

Drug level increased treatments and more:

How severe was Drug level increased and when was it recovered:

Expand to all the drugs that have ingredients of tobramycin:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Tobi podhaler:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Drug level increased:

Browse all the conditions that are associated with Drug level increased:


How the study uses the data?

The study uses data from the FDA. It is based on tobramycin (the active ingredients of Tobi podhaler) and Tobi podhaler (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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