Tobi and Sinus congestion - a phase IV clinical study of FDA data

Summary:

Sinus congestion is reported as a side effect among people who take Tobi (tobramycin), especially for people who are female, 30-39 old, have been taking the drug for < 1 month also take Pulmozyme, and have Cystic fibrosis.

The phase IV clinical study analyzes which people have Sinus congestion when taking Tobi. It is created by eHealthMe based on reports of 9,996 people who have side effects when taking Tobi from the FDA, and is updated regularly.

What is Tobi?

Tobi has active ingredients of tobramycin. eHealthMe is studying from 10,011 Tobi users. Check the latest studies of Tobi.

What is Sinus congestion?

Sinus congestion (blockage of sinus) is found to be associated with 1,006 drugs and 955 conditions by eHealthMe. Check the latest studies of Sinus congestion.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 02, 2026

9,996 people reported to have side effects when taking Tobi.
Among them, 31 people (0.31%) have Sinus congestion.

Among these 31 people:

How long have people been on Tobi when they have Sinus congestion? *

What is the gender of people who have Sinus congestion when taking Tobi? *

female: 58.06 %
male: 41.94 %

What is the age of people who have Sinus congestion when taking Tobi? *

What are other drugs people take besides Tobi? *

What are other side effects people have besides Sinus congestion? *

Cough: 20 people, 64.52%
Sputum Discolored: 14 people, 45.16%
Infective Pulmonary Exacerbation Of Cystic Fibrosis (severe infective lung disease with production of abnormally thick mucus): 13 people, 41.94%
Sputum Increased: 12 people, 38.71%
Dyspnea (difficult or laboured breathing): 10 people, 32.26%
Wheezing (a high-pitched whistling sound made while you breath): 9 people, 29.03%
Productive Cough: 9 people, 29.03%
Fatigue (feeling of tiredness): 9 people, 29.03%
Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 8 people, 25.81%
Coughing Up Blood: 8 people, 25.81%

What are the existing conditions these people have? *

Cystic Fibrosis (disease of the secretary glands): 24 people, 77.42%
Pseudomonas Infection (pseudomonas infection is caused by a bacterium, pseudomonas aeruginosa): 14 people, 45.16%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 8 people, 25.81%
Bronchiectasis (abnormal widening of the bronchi or their branches, causing a risk of infection): 7 people, 22.58%
Sinusitis (inflammation of sinus): 5 people, 16.13%
Sinus Disorder (disease of sinus): 5 people, 16.13%
Cystic Fibrosis Lung (fibrosis with cyst in the lung): 5 people, 16.13%
Constipation: 5 people, 16.13%
Lung Infection Pseudomonal (bacterial infection of lung by pseudomonas aeruginosa): 5 people, 16.13%
Obsessive-Compulsive Disorder (an anxiety disorder characterized by intrusive thoughts that produce uneasiness, apprehension, fear, or worry;): 4 people, 12.90%

* Approximation only. Some reports may have incomplete information.

Do you take Tobi and have Sinus congestion?

- Check whether Sinus congestion is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Tobi:

Tobi (10,011 reports)

Sinus congestion treatments and more:

Sinus congestion (21,241 reports)

Browse all side effects of Tobi:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Sinus congestion:

Sinus congestion (1,006 drugs)

Browse all the conditions that are associated with Sinus congestion:

Sinus congestion (955 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on tobramycin (the active ingredients of Tobi) and Tobi (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.