Topamax and Gallbladder non-functioning - a phase IV clinical study of FDA data

Summary:

Gallbladder non-functioning is reported as a side effect among people who take Topamax (topiramate), especially for people who are female, 10-19 old, have been taking the drug for 1 - 2 years also take Yasmin, and have Premenstrual syndrome.

The phase IV clinical study analyzes which people have Gallbladder non-functioning when taking Topamax. It is created by eHealthMe based on reports of 54,158 people who have side effects when taking Topamax from the FDA, and is updated regularly.

What is Topamax?

Topamax has active ingredients of topiramate. It is often used in migraine. eHealthMe is studying from 58,954 Topamax users. Check the latest studies of Topamax.

What is Gallbladder non-functioning?

Gallbladder non-functioning is found to be associated with 117 drugs and 440 conditions by eHealthMe. Check the latest studies of Gallbladder non-functioning.

On Feb, 04, 2026

54,158 people reported to have side effects when taking Topamax.
Among them, 11 people (0.02%) have Gallbladder non-functioning.

Could Topamax cause Gallbladder non-functioning?

Among these 11 people:

How long have people been on Topamax when they have Gallbladder non-functioning? *

What is the gender of people who have Gallbladder non-functioning when taking Topamax? *

female: 81.82 %
male: 18.18 %

What is the age of people who have Gallbladder non-functioning when taking Topamax? *

What are other drugs people take besides Topamax? *

Yasmin: 11 people, 100.00%
Ranitidine: 4 people, 36.36%
Yaz: 4 people, 36.36%
Zantac: 4 people, 36.36%
Tylenol W/ Codeine No. 3: 4 people, 36.36%
Naproxen: 4 people, 36.36%
Drospirenone And Ethinyl Estradiol: 4 people, 36.36%
Reglan: 3 people, 27.27%
Phenergan: 3 people, 27.27%
Darvocet: 3 people, 27.27%

What are other side effects people have besides Gallbladder non-functioning? *

Pain: 11 people, 100.00%
Cholecystitis Chronic (long lasting infection of gallbladder): 9 people, 81.82%
Biliary Dyskinesia (motility disorder that affects the gallbladder and sphincter of oddi): 5 people, 45.45%
Diarrhea: 4 people, 36.36%
Pulmonary Embolism (blockage of the main artery of the lung): 4 people, 36.36%
Abdominal Pain Upper: 4 people, 36.36%
Appendicitis Perforated (perforated appendicitis is a condition in which an inflamed appendix bursts): 4 people, 36.36%
Nausea And Vomiting: 4 people, 36.36%
Injury: 4 people, 36.36%
Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 4 people, 36.36%

What are the existing conditions these people have? *

Premenstrual Syndrome: 8 people, 72.73%
Acne (skin problems that cause pimples): 5 people, 45.45%
Multiple Allergies (allergy to multiple agents): 2 people, 18.18%
Clonic Convulsion (long lasting seizure): 2 people, 18.18%
Birth Control: 2 people, 18.18%
Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 1 person, 9.09%
Premenstrual Dysphoric Disorder: 1 person, 9.09%
Polycystic Ovary Disease (cysts in the ovaries that occurs when the follicle stops developing): 1 person, 9.09%
Pelvic Pain: 1 person, 9.09%
Ovarian Cysts (fluid filled sacs of the ovary): 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Topamax and have Gallbladder non-functioning?

- Check whether Gallbladder non-functioning is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Topamax:

Topamax (58,954 reports)

Browse all side effects of Topamax:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Gallbladder non-functioning:

Gallbladder non-functioning (117 drugs)

Browse all the conditions that are associated with Gallbladder non-functioning:

Gallbladder non-functioning (440 conditions)

Related publications that referenced our studies

Baloch M, Siddiqui MA, "Topiramate induced sudden loss of vision", JPMA, 2012 Oct .
Kocamaz, M., & Karadag, O., "Topiramate-Induced Acute Myopia, Diplopia, and Photosensitivity: A Case Report", Beyoglu Eye Journal, 2019 Jan .
Baloch M, Siddiqui MA, "Topiramate induced sudden loss of vision", JPMA, 2012 Oct .
Kocamaz, M., & Karadag, O., "Topiramate-Induced Acute Myopia, Diplopia, and Photosensitivity: A Case Report", Beyoglu Eye Journal, 2019 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on topiramate (the active ingredients of Topamax) and Topamax (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.