Topamax and Spinal column stenosis - a phase IV clinical study of FDA data

Summary:

Spinal column stenosis is reported as a side effect among people who take Topamax (topiramate), especially for people who are female, 60+ old, have been taking the drug for 1 - 2 years also take Protonix, and have Pain.

The phase IV clinical study analyzes which people have Spinal column stenosis when taking Topamax. It is created by eHealthMe based on reports of 54,158 people who have side effects when taking Topamax from the FDA, and is updated regularly.

What is Topamax?

Topamax has active ingredients of topiramate. It is often used in migraine. eHealthMe is studying from 58,954 Topamax users. Check the latest studies of Topamax.

What is Spinal column stenosis?

Spinal column stenosis (narrowing of spinal column) is found to be associated with 841 drugs and 739 conditions by eHealthMe. Check the latest studies of Spinal column stenosis.

On Jul, 17, 2026

54,158 people reported to have side effects when taking Topamax.
Among them, 60 people (0.11%) have Spinal column stenosis.

Could Topamax cause Spinal column stenosis?

Among these 60 people:

How long have people been on Topamax when they have Spinal column stenosis? *

What is the gender of people who have Spinal column stenosis when taking Topamax? *

female: 86.44 %
male: 13.56 %

What is the age of people who have Spinal column stenosis when taking Topamax? *

What are other drugs people take besides Topamax? *

What are other side effects people have besides Spinal column stenosis? *

Stress And Anxiety: 25 people, 41.67%
Intervertebral Disc Protrusion (spinal disc protrusion): 22 people, 36.67%
Dizziness: 21 people, 35.00%
Pain: 21 people, 35.00%
Depression: 18 people, 30.00%
Weight Increased: 17 people, 28.33%
Intervertebral Disc Degeneration (spinal disc degeneration): 16 people, 26.67%
Nausea (feeling of having an urge to vomit): 15 people, 25.00%
Swallowing Difficulty: 15 people, 25.00%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 14 people, 23.33%

What are the existing conditions these people have? *

Pain: 7 people, 11.67%
Neuropathy Peripheral (surface nerve damage): 6 people, 10.00%
Fibromyalgia (a long-term condition which causes pain all over the body): 5 people, 8.33%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 8.33%
Restless Leg Syndrome (a powerful urge to move your legs): 4 people, 6.67%
High Blood Pressure: 4 people, 6.67%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 4 people, 6.67%
Post Herpetic Neuralgia (neuralgia caused by the varicella zoster virus): 4 people, 6.67%
Osteoporosis (bones weak and more likely to break): 4 people, 6.67%
Stress And Anxiety: 4 people, 6.67%

* Approximation only. Some reports may have incomplete information.

Do you take Topamax and have Spinal column stenosis?

- Check whether Spinal column stenosis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Topamax:

Topamax (58,954 reports)

Browse all side effects of Topamax:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Spinal column stenosis:

Spinal column stenosis (841 drugs)

Browse all the conditions that are associated with Spinal column stenosis:

Spinal column stenosis (739 conditions)

Related publications that referenced our studies

Baloch M, Siddiqui MA, "Topiramate induced sudden loss of vision", JPMA, 2012 Oct .
Kocamaz, M., & Karadag, O., "Topiramate-Induced Acute Myopia, Diplopia, and Photosensitivity: A Case Report", Beyoglu Eye Journal, 2019 Jan .
Baloch M, Siddiqui MA, "Topiramate induced sudden loss of vision", JPMA, 2012 Oct .
Kocamaz, M., & Karadag, O., "Topiramate-Induced Acute Myopia, Diplopia, and Photosensitivity: A Case Report", Beyoglu Eye Journal, 2019 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on topiramate (the active ingredients of Topamax) and Topamax (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.