Toprol-xl and Bladder disorder - a phase IV clinical study of FDA data

Summary:

Bladder disorder is reported as a side effect among people who take Toprol-xl (metoprolol succinate), especially for people who are female, 60+ old, have been taking the drug for 2 - 5 years also take Lipitor, and have Multiple sclerosis.

The phase IV clinical study analyzes which people have Bladder disorder when taking Toprol-xl. It is created by eHealthMe based on reports of 38,273 people who have side effects when taking Toprol-xl from the FDA, and is updated regularly.

What is Toprol-xl?

Toprol-xl has active ingredients of metoprolol succinate. It is often used in high blood pressure. eHealthMe is studying from 40,636 Toprol-xl users. Check the latest studies of Toprol-xl.

What is Bladder disorder?

Bladder disorder is found to be associated with 906 drugs and 894 conditions by eHealthMe. Check the latest studies of Bladder disorder.



On Jul, 17, 2026

38,273 people reported to have side effects when taking Toprol-xl.
Among them, 73 people (0.19%) have Bladder disorder.

Could Toprol-xl cause Bladder disorder?

Among these 73 people:

How long have people been on Toprol-xl when they have Bladder disorder? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 66.67 %
  • 5 - 10 years: 33.33 %
  • 10+ years: 0.0 %

What is the gender of people who have Bladder disorder when taking Toprol-xl? *

  • female: 62.5 %
  • male: 37.5 %

What is the age of people who have Bladder disorder when taking Toprol-xl? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 3.28 %
  • 30-39: 0.0 %
  • 40-49: 16.39 %
  • 50-59: 24.59 %
  • 60+: 55.74 %

What are other drugs people take besides Toprol-xl? *

  1. Norvasc: 19 people, 26.03%
  2. Lipitor: 19 people, 26.03%
  3. Aspirin: 16 people, 21.92%
  4. Vioxx: 15 people, 20.55%
  5. Zocor: 15 people, 20.55%
  6. Diovan: 15 people, 20.55%
  7. Lasix: 14 people, 19.18%
  8. Plavix: 14 people, 19.18%
  9. Synthroid: 13 people, 17.81%
  10. Neurontin: 12 people, 16.44%

What are other side effects people have besides Bladder disorder? *

  1. Chest Pain: 22 people, 30.14%
  2. Sinusitis (inflammation of sinus): 22 people, 30.14%
  3. Urinary Tract Infection: 19 people, 26.03%
  4. Fatigue (feeling of tiredness): 18 people, 24.66%
  5. Weight Decreased: 16 people, 21.92%
  6. Pain: 16 people, 21.92%
  7. Acute Kidney Failure: 15 people, 20.55%
  8. Headache (pain in head): 15 people, 20.55%
  9. Cough: 15 people, 20.55%
  10. Muscle Aches (muscle pain): 14 people, 19.18%

What are the existing conditions these people have? *

  1. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 7 people, 9.59%
  2. Pain: 6 people, 8.22%
  3. High Blood Cholesterol: 6 people, 8.22%
  4. Arthritis (form of joint disorder that involves inflammation of one or more joints): 6 people, 8.22%
  5. Fatigue (feeling of tiredness): 5 people, 6.85%
  6. Osteoporosis (bones weak and more likely to break): 5 people, 6.85%
  7. Depression: 5 people, 6.85%
  8. Osteoarthritis (a joint disease caused by cartilage loss in a joint): 4 people, 5.48%
  9. Anaemia Of Malignant Disease: 3 people, 4.11%
  10. Hyperlipidaemia (presence of excess lipids in the blood): 3 people, 4.11%

* Approximation only. Some reports may have incomplete information.

Do you take Toprol-xl and have Bladder disorder?

- Check whether Bladder disorder is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Toprol-xl:

Bladder disorder treatments and more:

How severe was Bladder disorder and when was it recovered:

Expand to all the drugs that have ingredients of metoprolol succinate:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Toprol-xl:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Bladder disorder:

Browse all the conditions that are associated with Bladder disorder:


How the study uses the data?

The study uses data from the FDA. It is based on metoprolol succinate (the active ingredients of Toprol-xl) and Toprol-xl (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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