Tpn and Acute kidney failure - a phase IV clinical study of FDA data

Summary:

Acute kidney failure is reported as a side effect among people who take Tpn (niacinamide; pyridoxine hydrochloride; tyrosine), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Sodium Chloride, and have Short-bowel syndrome.

The phase IV clinical study analyzes which people have Acute kidney failure when taking Tpn. It is created by eHealthMe based on reports of 1,568 people who have side effects when taking Tpn from the FDA, and is updated regularly.

What is Tpn?

Tpn has active ingredients of niacinamide; pyridoxine hydrochloride; tyrosine. eHealthMe is studying from 1,581 Tpn users. Check the latest studies of Tpn.

What is Acute kidney failure?

Acute kidney failure is found to be associated with 2,835 drugs and 4,492 conditions by eHealthMe. Check the latest studies of Acute kidney failure.

On Jul, 14, 2026

1,568 people reported to have side effects when taking Tpn.
Among them, 27 people (1.72%) have Acute kidney failure.

Among these 27 people:

How long have people been on Tpn when they have Acute kidney failure? *

What is the gender of people who have Acute kidney failure when taking Tpn? *

female: 58.33 %
male: 41.67 %

What is the age of people who have Acute kidney failure when taking Tpn? *

What are other drugs people take besides Tpn? *

What are other side effects people have besides Acute kidney failure? *

Weight Decreased: 8 people, 29.63%
Diarrhea: 7 people, 25.93%
Weakness: 7 people, 25.93%
Muscle Spasms (muscle contraction): 7 people, 25.93%
Fall: 6 people, 22.22%
Sepsis (a severe blood infection that can lead to organ failure and death): 6 people, 22.22%
Septic Shock (shock due to blood infection): 5 people, 18.52%
Flatulence (flatus expelled through the anus): 5 people, 18.52%
Peripheral Swelling: 5 people, 18.52%
Abdominal Distension: 5 people, 18.52%

What are the existing conditions these people have? *

Short-Bowel Syndrome (a condition in which the body cannot absorb enough fluids and nutrients because part of the small intestine is missing): 18 people, 66.67%
Pain: 5 people, 18.52%
Infection: 4 people, 14.81%
Malabsorption (a state arising from abnormality in absorption of food nutrients across the gastrointestinal (gi) tract): 3 people, 11.11%
Electrolyte Imbalance: 3 people, 11.11%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 11.11%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 2 people, 7.41%
Depression: 2 people, 7.41%
Immunodeficiency Common Variable: 2 people, 7.41%
Diarrhea: 2 people, 7.41%

* Approximation only. Some reports may have incomplete information.

Do you take Tpn and have Acute kidney failure?

- Check whether Acute kidney failure is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Tpn:

Tpn (1,581 reports)

Acute kidney failure treatments and more:

Acute kidney failure (259,717 reports)

How severe was Acute kidney failure and when was it recovered:

Acute kidney failure in Tpn

Expand to all the drugs that have ingredients of niacinamide; pyridoxine hydrochloride; tyrosine:

Acute kidney failure and drugs with ingredients of niacinamide; pyridoxine hydrochloride; tyrosine (41 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Tpn:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Acute kidney failure:

Acute kidney failure (2,835 drugs)

Browse all the conditions that are associated with Acute kidney failure:

Acute kidney failure (4,492 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on niacinamide; pyridoxine hydrochloride; tyrosine (the active ingredients of Tpn) and Tpn (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.