Tracleer and Hyponatremia - a phase IV clinical study of FDA data
Summary:
Hyponatremia is reported as a side effect among people who take Tracleer (bosentan), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Lasix, and have Pulmonary hypertension.
The phase IV clinical study analyzes which people have Hyponatremia when taking Tracleer. It is created by eHealthMe based on reports of 55,065 people who have side effects when taking Tracleer from the FDA, and is updated regularly.
What is Tracleer?
Tracleer has active ingredients of bosentan. It is often used in primary pulmonary hypertension. eHealthMe is studying from 55,125 Tracleer users. Check the latest studies of Tracleer.
What is Hyponatremia?
Hyponatremia (abnormally low level of sodium in the blood; associated with dehydration) is found to be associated with 1,957 drugs and 2,249 conditions by eHealthMe. Check the latest studies of Hyponatremia.
55,065 people reported to have side effects when taking Tracleer.
Among them, 145 people (0.26%) have Hyponatremia.
Among these 145 people:
How long have people been on Tracleer when they have Hyponatremia? *
What is the gender of people who have Hyponatremia when taking Tracleer? *
What is the age of people who have Hyponatremia when taking Tracleer? *
What are other drugs people take besides Tracleer? *
What are other side effects people have besides Hyponatremia? *
What are the existing conditions these people have? *
* Approximation only. Some reports may have incomplete information.
Do you take Tracleer and have Hyponatremia?
- Check whether Hyponatremia is associated with a drug or a condition (FREE)
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Related studies:
Effectiveness of, long term effects of, and alternative drugs to Tracleer:
- Tracleer (55,125 reports)
Hyponatremia treatments and more:
- Hyponatremia (72,436 reports)
How severe was Hyponatremia and when was it recovered:
Expand to all the drugs that have ingredients of bosentan:
Sub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Common Tracleer side effects:
- Tracleer side effect: Aspartate aminotransferase increased (2,589 reports)
Browse all side effects of Tracleer:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon drugs associated with Hyponatremia:
- Furosemide side effect: Hyponatremia (4,994 reports)
- Omeprazole side effect: Hyponatremia (4,506 reports)
- Aspirin side effect: Hyponatremia (4,113 reports)
- Amlodipine side effect: Hyponatremia (3,574 reports)
- Zide side effect: Hyponatremia (3,350 reports)
- Hydrochlorothiazide side effect: Hyponatremia (3,343 reports)
- Pantoprazole side effect: Hyponatremia (3,170 reports)
- Ramipril side effect: Hyponatremia (2,956 reports)
- Metformin side effect: Hyponatremia (2,879 reports)
- Simvastatin side effect: Hyponatremia (2,773 reports)
Browse all the drugs that are associated with Hyponatremia:
- Hyponatremia (1,957 drugs)
Common conditions associated with Hyponatremia:
- Hypertension: 11,014 reports
- Blood pressure increased: 10,953 reports
- Depression: 5,215 reports
- Antidepressant therapy: 5,182 reports
- Pain: 2,387 reports
- Anxiety aggravated: 1,630 reports
- Anxiety, apprehension, feeling uptight, jitters, stress, stress and anxiety, tension: 1,629 reports
- Constipation: 1,615 reports
- Plasma cell myeloma: 1,461 reports
- Atrial flutter: 1,443 reports
Browse all the conditions that are associated with Hyponatremia:
- Hyponatremia (2,249 conditions)
Related publications that referenced our studies
- Choi N, Lee JY, Sunwoo JS, Kwon KI, Roh H, Ahn MY, Lee KB, "Hyponatremia during Acyclovir Treatment of Bell’s Palsy", Journal of the Korean Neurological Association, 2017 Aug .
- Koza Y, Ta? MH, ?im?ek Z, Gündo?du F, "Hyponatremia and heart failure: the overlooked piece of the puzzle", Anatolian journal of cardiology, 2016 Jan .
- Das S, Bandyopadhyay S, Ramasamy A, Prabhu VV, Pachiappan S, "A case of losartan-induced severe hyponatremia", Journal of pharmacology & pharmacotherapeutics, 2015 Jan .
- Gupta E, Kunjal R, Cury JD, "Severe hyponatremia due to valproic acid toxicity", Journal of clinical medicine research, 2015 Jan .
- Kate N, Grover S, Kumar S, Modi M, "Bupropion-induced hyponatremia", General hospital psychiatry, 2013 Dec .
- Choi N, Lee JY, Sunwoo JS, Kwon KI, Roh H, Ahn MY, Lee KB, "Hyponatremia during Acyclovir Treatment of Bell’s Palsy", Journal of the Korean Neurological Association, 2017 Aug .
- Koza Y, Ta? MH, ?im?ek Z, Gündo?du F, "Hyponatremia and heart failure: the overlooked piece of the puzzle", Anatolian journal of cardiology, 2016 Jan .
- Das S, Bandyopadhyay S, Ramasamy A, Prabhu VV, Pachiappan S, "A case of losartan-induced severe hyponatremia", Journal of pharmacology & pharmacotherapeutics, 2015 Jan .
- Gupta E, Kunjal R, Cury JD, "Severe hyponatremia due to valproic acid toxicity", Journal of clinical medicine research, 2015 Jan .
- Kate N, Grover S, Kumar S, Modi M, "Bupropion-induced hyponatremia", General hospital psychiatry, 2013 Dec .
How the study uses the data?
The study uses data from the FDA. It is based on bosentan (the active ingredients of Tracleer) and Tracleer (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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