Trandate and Stroke - a phase IV clinical study of FDA data

Summary:

Stroke is reported as a side effect among people who take Trandate (labetalol hydrochloride), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Norvasc, and have Diabetes.

The phase IV clinical study analyzes which people have Stroke when taking Trandate. It is created by eHealthMe based on reports of 1,703 people who have side effects when taking Trandate from the FDA, and is updated regularly.

What is Trandate?

Trandate has active ingredients of labetalol hydrochloride. It is often used in high blood pressure. eHealthMe is studying from 1,735 Trandate users. Check the latest studies of Trandate.

What is Stroke?

Stroke (sudden death of a portion of the brain cells due to a lack of oxygen) is found to be associated with 2,335 drugs and 3,028 conditions by eHealthMe. Check the latest studies of Stroke.



On Jun, 19, 2026

1,703 people reported to have side effects when taking Trandate.
Among them, 27 people (1.59%) have Stroke.

Could Trandate cause Stroke?

Among these 27 people:

How long have people been on Trandate when they have Stroke? *

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Stroke when taking Trandate? *

  • female: 59.09 %
  • male: 40.91 %

What is the age of people who have Stroke when taking Trandate? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 15 %
  • 50-59: 5 %
  • 60+: 80 %

What are other drugs people take besides Trandate? *

  1. Norvasc: 13 people, 48.15%
  2. Levemir: 8 people, 29.63%
  3. Crestor: 8 people, 29.63%
  4. Lasix: 8 people, 29.63%
  5. Plavix: 7 people, 25.93%
  6. Avandia: 7 people, 25.93%
  7. Celexa: 6 people, 22.22%
  8. Nitroglycerin: 6 people, 22.22%
  9. Colace: 6 people, 22.22%
  10. Neurontin: 5 people, 18.52%

What are other side effects people have besides Stroke? *

  1. Transient Ischaemic Attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow)): 7 people, 25.93%
  2. Cerebral Haemorrhage (bleeding within the brain): 6 people, 22.22%
  3. Visual Impairment: 5 people, 18.52%
  4. Multiple Sclerosis Relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 5 people, 18.52%
  5. Acute Kidney Failure: 5 people, 18.52%
  6. Urinary Incontinence (inability to control the flow of urine and involuntary urination): 5 people, 18.52%
  7. Impaired Driving Ability: 5 people, 18.52%
  8. Thrombocytopenia (decrease of platelets in blood): 5 people, 18.52%
  9. White Blood Cell Count Decreased: 4 people, 14.81%
  10. Dyspnea (difficult or laboured breathing): 4 people, 14.81%

What are the existing conditions these people have? *

  1. Diabetes: 8 people, 29.63%
  2. Pain: 5 people, 18.52%
  3. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 5 people, 18.52%
  4. Chronic Myeloid Leukaemia (long lasting type of cancer that starts in the blood-forming cells of the bone marrow and invades the blood): 3 people, 11.11%
  5. Depression: 3 people, 11.11%
  6. Paranoia (psychotic disorder characterized by delusions of persecution with or without grandeur): 2 people, 7.41%
  7. Mental Disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability): 2 people, 7.41%
  8. Hyperlipidaemia (presence of excess lipids in the blood): 2 people, 7.41%
  9. Diabetic Retinopathy (damage to the retina caused by complications of diabetes): 2 people, 7.41%
  10. Diabetic Retinal Oedema (excessive build-up of fluid in the retina due to diabetes): 2 people, 7.41%

* Approximation only. Some reports may have incomplete information.

Do you take Trandate and have Stroke?

- Check whether Stroke is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Trandate:

Stroke treatments and more:

How severe was Stroke and when was it recovered:

Expand to all the drugs that have ingredients of labetalol hydrochloride:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Trandate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Stroke:

Browse all the conditions that are associated with Stroke:


How the study uses the data?

The study uses data from the FDA. It is based on labetalol hydrochloride (the active ingredients of Trandate) and Trandate (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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