Trandolapril and Crohn's disease - a phase IV clinical study of FDA data

Summary:

Crohn's disease is reported as a side effect among people who take Trandolapril (trandolapril), especially for people who are male, 60+ old, also take Ondansetron, and have Ulcerative colitis.

The phase IV clinical study analyzes which people have Crohn's disease when taking Trandolapril. It is created by eHealthMe based on reports of 2,634 people who have side effects when taking Trandolapril from the FDA, and is updated regularly.

What is Trandolapril?

Trandolapril has active ingredients of trandolapril. It is often used in high blood pressure. eHealthMe is studying from 2,682 Trandolapril users. Check the latest studies of Trandolapril.

What is Crohn's disease?

Crohn's disease (a condition that causes inflammation of the gastrointestinal tract) is found to be associated with 1,352 drugs and 2,077 conditions by eHealthMe. Check the latest studies of Crohn's disease.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 01, 2026

2,634 people reported to have side effects when taking Trandolapril.
Among them, 22 people (0.84%) have Crohn's disease.

Could Trandolapril cause Crohn's disease?

Among these 22 people:

What is the gender of people who have Crohn's disease when taking Trandolapril? *

female: 38.1 %
male: 61.9 %

What is the age of people who have Crohn's disease when taking Trandolapril? *

What are other drugs people take besides Trandolapril? *

What are other side effects people have besides Crohn's disease? *

Abdominal Pain: 13 people, 59.09%
Abdominal Distension: 10 people, 45.45%
Night Sweats (sweating in night): 9 people, 40.91%
Cough: 9 people, 40.91%
Diarrhea: 7 people, 31.82%
Malaise (a feeling of general discomfort or uneasiness): 6 people, 27.27%
C-Reactive Protein Increased: 5 people, 22.73%
Canker Sores (painful, open sore in the mouth): 5 people, 22.73%
Drug Specific Antibody Present: 5 people, 22.73%
Gastrointestinal Disorder (functional problems of gastrointestinal tract): 5 people, 22.73%

What are the existing conditions these people have? *

Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 3 people, 13.64%
Metastases To Bone (cancer spreads to bone): 1 person, 4.55%
Breast Cancer Metastatic: 1 person, 4.55%

* Approximation only. Some reports may have incomplete information.

Do you take Trandolapril and have Crohn's disease?

- Check whether Crohn's disease is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Trandolapril:

Trandolapril (2,682 reports)

Crohn's disease treatments and more:

Crohn's disease (390,234 reports)

Browse all side effects of Trandolapril:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Crohn's disease:

Crohn's disease (1,352 drugs)

Browse all the conditions that are associated with Crohn's disease:

Crohn's disease (2,077 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on trandolapril (the active ingredients of Trandolapril) and Trandolapril (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.