Tranxene and Aggression - a phase IV clinical study of FDA data
Summary:
Aggression is reported as a side effect among people who take Tranxene (clorazepate dipotassium), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Pregabalin, and have Allergic rhinitis.
The phase IV clinical study analyzes which people have Aggression when taking Tranxene. It is created by eHealthMe based on reports of 6,399 people who have side effects when taking Tranxene from the FDA, and is updated regularly.
What is Tranxene?
Tranxene has active ingredients of clorazepate dipotassium. It is often used in stress and anxiety. eHealthMe is studying from 6,550 Tranxene users. Check the latest studies of Tranxene.
What is Aggression?
Aggression is found to be associated with 1,551 drugs and 1,964 conditions by eHealthMe. Check the latest studies of Aggression.
6,399 people reported to have side effects when taking Tranxene.
Among them, 71 people (1.11%) have Aggression.

Among these 71 people:
How long have people been on Tranxene when they have Aggression? *
- < 1 month: 81.82 %
- 1 - 6 months: 9.09 %
- 6 - 12 months: 0.0 %
- 1 - 2 years: 0.0 %
- 2 - 5 years: 9.09 %
- 5 - 10 years: 0.0 %
- 10+ years: 0.0 %
What is the gender of people who have Aggression when taking Tranxene? *
- female: 43.66 %
- male: 56.34 %
What is the age of people who have Aggression when taking Tranxene? *
- 0-1: 0.0 %
- 2-9: 1.67 %
- 10-19: 6.67 %
- 20-29: 18.33 %
- 30-39: 16.67 %
- 40-49: 11.67 %
- 50-59: 10.0 %
- 60+: 35.0 %
What are other drugs people take besides Tranxene? *
- Zyprexa: 8 people, 11.27%
- Pregabalin: 8 people, 11.27%
- Prozac: 6 people, 8.45%
- Lasix: 6 people, 8.45%
- Cymbalta: 5 people, 7.04%
- Buspirone Hydrochloride: 5 people, 7.04%
- Paxil: 4 people, 5.63%
- Wellbutrin: 4 people, 5.63%
- Acetaminophen: 4 people, 5.63%
- Lamictal: 4 people, 5.63%
What are other side effects people have besides Aggression? *
- Agitation (state of anxiety or nervous excitement): 21 people, 29.58%
- Confusional State: 19 people, 26.76%
- Sedation: 17 people, 23.94%
- Confusion: 15 people, 21.13%
- Tremor (trembling or shaking movements in one or more parts of your body): 15 people, 21.13%
- Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down): 13 people, 18.31%
- Drowsiness: 13 people, 18.31%
- Fall: 11 people, 15.49%
- Neuroleptic Malignant Syndrome (a life-threatening neurological disorder most often caused by an adverse reaction to neuroleptic or antipsychotic agents): 11 people, 15.49%
- Speech Impairment (Adult) (inability to speak (adult)): 11 people, 15.49%
What are the existing conditions these people have? *
- Extrapyramidal Disorder (involuntary muscle spasms in the face and neck): 9 people, 12.68%
- Schizoaffective Disorder (a mental disorder characterized by disordered thought): 9 people, 12.68%
- Allergic Rhinitis: 9 people, 12.68%
- Depression: 8 people, 11.27%
- Parkinson's Disease: 3 people, 4.23%
- Abnormal Behavior: 2 people, 2.82%
- Attention Deficit Hyperactivity Disorder (a chronic condition including attention difficulty, hyperactivity, and impulsiveness): 2 people, 2.82%
- Constipation: 2 people, 2.82%
- Bipolar Ii Disorder (characterized by at least one episode of hypomania and at least one episode of major depression): 2 people, 2.82%
- High Blood Pressure: 2 people, 2.82%
* Approximation only. Some reports may have incomplete information.
Do you take Tranxene and have Aggression?
- Check whether Aggression is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, long term effects of, and alternative drugs to Tranxene:
- Tranxene (6,550 reports)
Aggression treatments and more:
- Aggression (65,312 reports)
How severe was Aggression and when was it recovered:
Expand to all the drugs that have ingredients of clorazepate dipotassium:
Sub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Tranxene:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all the drugs that are associated with Aggression:
- Aggression (1,551 drugs)
Browse all the conditions that are associated with Aggression:
- Aggression (1,964 conditions)
How the study uses the data?
The study uses data from the FDA. It is based on clorazepate dipotassium (the active ingredients of Tranxene) and Tranxene (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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