Trental and Colitis - a phase IV clinical study of FDA data

Summary:

Colitis is reported as a side effect among people who take Trental (pentoxifylline), especially for people who are male, 60+ old, also take Betapace, and have Fatigue.

The phase IV clinical study analyzes which people have Colitis when taking Trental. It is created by eHealthMe based on reports of 3,456 people who have side effects when taking Trental from the FDA, and is updated regularly.

What is Trental?

Trental has active ingredients of pentoxifylline. eHealthMe is studying from 3,511 Trental users. Check the latest studies of Trental.

What is Colitis?

Colitis (inflammation of colon) is found to be associated with 1,597 drugs and 1,523 conditions by eHealthMe. Check the latest studies of Colitis.



On Jul, 14, 2026

3,456 people reported to have side effects when taking Trental.
Among them, 12 people (0.35%) have Colitis.

Could Trental cause Colitis?

Among these 12 people:

What is the gender of people who have Colitis when taking Trental? *

  • female: 41.67 %
  • male: 58.33 %

What is the age of people who have Colitis when taking Trental? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 9.09 %
  • 50-59: 0.0 %
  • 60+: 90.91 %

What are other drugs people take besides Trental? *

  1. Zoloft: 2 people, 16.67%
  2. Lasix: 2 people, 16.67%
  3. Aredia: 2 people, 16.67%
  4. Synthroid: 2 people, 16.67%
  5. Betapace: 2 people, 16.67%
  6. Zometa: 1 person, 8.33%
  7. Cefotaxime: 1 person, 8.33%
  8. Folic Acid: 1 person, 8.33%
  9. Doxycycline: 1 person, 8.33%
  10. Dilaudid: 1 person, 8.33%

What are other side effects people have besides Colitis? *

  1. Glaucoma (increased fluid pressure in the eye with vision loss): 3 people, 25.00%
  2. Diarrhea: 2 people, 16.67%
  3. Urinary Retention (the inability to completely or partially empty the bladder): 2 people, 16.67%
  4. Joint Pain: 2 people, 16.67%
  5. Retinal Artery Thrombosis (blood clot in retinal artery): 2 people, 16.67%
  6. Retinal Vessel Occlusion (a blockage in one of the small arteries): 2 people, 16.67%
  7. Gastric Disorder (disease of stomach): 1 person, 8.33%
  8. Exostosis (formation of new bone on the surface of a bone): 1 person, 8.33%
  9. Eye Pain: 1 person, 8.33%
  10. Faecaluria (faeces with urine from urethra): 1 person, 8.33%

What are the existing conditions these people have? *

  1. Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 1 person, 8.33%
  2. Neuralgia (pain in one or more nerves): 1 person, 8.33%
  3. Muscle Rigidity (muscle stiffness): 1 person, 8.33%
  4. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 1 person, 8.33%
  5. Multiple Myeloma (cancer of the plasma cells): 1 person, 8.33%
  6. Lung Neoplasm Malignant (cancer tumour of lung): 1 person, 8.33%
  7. Gait Disturbance: 1 person, 8.33%
  8. Fatigue (feeling of tiredness): 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Trental and have Colitis?

- Check whether Colitis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Trental:

Colitis treatments and more:

How severe was Colitis and when was it recovered:

Expand to all the drugs that have ingredients of pentoxifylline:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Trental:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Colitis:

Browse all the conditions that are associated with Colitis:


How the study uses the data?

The study uses data from the FDA. It is based on pentoxifylline (the active ingredients of Trental) and Trental (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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