Trental and Cough - a phase IV clinical study of FDA data

Summary:

Cough is reported as a side effect among people who take Trental (pentoxifylline), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Aspirin, and have Interstitial lung disease.

The phase IV clinical study analyzes which people have Cough when taking Trental. It is created by eHealthMe based on reports of 3,456 people who have side effects when taking Trental from the FDA, and is updated regularly.

What is Trental?

Trental has active ingredients of pentoxifylline. eHealthMe is studying from 3,511 Trental users. Check the latest studies of Trental.

What is Cough?

Cough is found to be associated with 3,048 drugs and 3,804 conditions by eHealthMe. Check the latest studies of Cough.



On Aug, 07, 2026

3,456 people reported to have side effects when taking Trental.
Among them, 99 people (2.86%) have Cough.

Could Trental cause Cough?

Among these 99 people:

How long have people been on Trental when they have Cough? *

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Cough when taking Trental? *

  • female: 43.82 %
  • male: 56.18 %

What is the age of people who have Cough when taking Trental? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 8.0 %
  • 50-59: 37.33 %
  • 60+: 54.67 %

What are other drugs people take besides Trental? *

  1. Aspirin: 33 people, 33.33%
  2. Lasix: 30 people, 30.30%
  3. Celebrex: 25 people, 25.25%
  4. Lipitor: 24 people, 24.24%
  5. Plavix: 21 people, 21.21%
  6. Diflucan: 21 people, 21.21%
  7. Allopurinol: 21 people, 21.21%
  8. Prozac: 20 people, 20.20%
  9. Neurontin: 18 people, 18.18%
  10. Aredia: 18 people, 18.18%

What are other side effects people have besides Cough? *

  1. Dyspnea (difficult or laboured breathing): 49 people, 49.49%
  2. Pneumonia: 39 people, 39.39%
  3. Nausea (feeling of having an urge to vomit): 38 people, 38.38%
  4. Fatigue (feeling of tiredness): 38 people, 38.38%
  5. Haematuria (presence of blood in urine): 37 people, 37.37%
  6. Nausea And Vomiting: 37 people, 37.37%
  7. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 36 people, 36.36%
  8. Osteoporosis (bones weak and more likely to break): 32 people, 32.32%
  9. Stress And Anxiety: 32 people, 32.32%
  10. Weakness: 30 people, 30.30%

What are the existing conditions these people have? *

  1. Interstitial Lung Disease: 16 people, 16.16%
  2. Systemic Sclerosis (Scleroderma) (an autoimmune or connective tissue disease. it is characterized by thickening of the skin): 15 people, 15.15%
  3. Multiple Myeloma (cancer of the plasma cells): 11 people, 11.11%
  4. Raynaud's Phenomenon (discoloration of the fingers, toes, and occasionally other areas): 11 people, 11.11%
  5. Bone Disorder: 10 people, 10.10%
  6. Osteoporosis (bones weak and more likely to break): 7 people, 7.07%
  7. High Blood Cholesterol: 4 people, 4.04%
  8. Joint Pain: 4 people, 4.04%
  9. Light Chain Analysis Increased: 4 people, 4.04%
  10. Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 4 people, 4.04%

* Approximation only. Some reports may have incomplete information.

Do you take Trental and have Cough?

- Check whether Cough is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Trental:

Cough treatments and more:

  • Cough (361,792 reports)

How severe was Cough and when was it recovered:

Expand to all the drugs that have ingredients of pentoxifylline:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Trental:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Cough:

Browse all the conditions that are associated with Cough:

  • Cough (3,804 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on pentoxifylline (the active ingredients of Trental) and Trental (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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