Tri-sprintec and Chest pain - a phase IV clinical study of FDA data

Summary:

Chest pain is reported as a side effect among people who take Tri-sprintec (ethinyl estradiol; norgestimate), especially for people who are female, 20-29 old, have been taking the drug for < 1 month also take Yasmin, and have Pain.

The phase IV clinical study analyzes which people have Chest pain when taking Tri-sprintec. It is created by eHealthMe based on reports of 1,038 people who have side effects when taking Tri-sprintec from the FDA, and is updated regularly.

What is Tri-sprintec?

Tri-sprintec has active ingredients of ethinyl estradiol; norgestimate. It is often used in birth control. eHealthMe is studying from 1,428 Tri-sprintec users. Check the latest studies of Tri-sprintec.

What is Chest pain?

Chest pain is found to be associated with 3,466 drugs and 4,888 conditions by eHealthMe. Check the latest studies of Chest pain.

On Jul, 12, 2026

1,038 people reported to have side effects when taking Tri-sprintec.
Among them, 28 people (2.7%) have Chest pain.

Among these 28 people:

How long have people been on Tri-sprintec when they have Chest pain? *

What is the gender of people who have Chest pain when taking Tri-sprintec? *

female: 96.43 %
male: 3.57 %

What is the age of people who have Chest pain when taking Tri-sprintec? *

What are other drugs people take besides Tri-sprintec? *

What are other side effects people have besides Chest pain? *

Dyspnea (difficult or laboured breathing): 13 people, 46.43%
Gallstones (stone formation by bile component): 9 people, 32.14%
Abdominal Pain Upper: 7 people, 25.00%
Dizziness: 7 people, 25.00%
Pain: 7 people, 25.00%
Cholecystitis Chronic (long lasting infection of gallbladder): 6 people, 21.43%
Nausea (feeling of having an urge to vomit): 6 people, 21.43%
Headache (pain in head): 5 people, 17.86%
Fatigue (feeling of tiredness): 4 people, 14.29%
High Blood Pressure: 3 people, 10.71%

What are the existing conditions these people have? *

Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 3 people, 10.71%
Pain: 3 people, 10.71%
Premenstrual Syndrome: 2 people, 7.14%
Nausea (feeling of having an urge to vomit): 2 people, 7.14%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 2 people, 7.14%
Behcet's Syndrome (involves inflammation of the blood vessels): 2 people, 7.14%
Thyroid Cancer: 1 person, 3.57%
Respiratory Tract Congestion (blockage on respiratory system): 1 person, 3.57%
Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 1 person, 3.57%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 1 person, 3.57%

* Approximation only. Some reports may have incomplete information.

Do you take Tri-sprintec and have Chest pain?

- Check whether Chest pain is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Tri-sprintec:

Tri-sprintec (1,428 reports)

Chest pain treatments and more:

Chest pain (363,501 reports)

How severe was Chest pain and when was it recovered:

Chest pain in Tri-sprintec

Expand to all the drugs that have ingredients of ethinyl estradiol; norgestimate:

Chest pain and drugs with ingredients of ethinyl estradiol; norgestimate (421 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Tri-sprintec:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Chest pain:

Chest pain (3,466 drugs)

Browse all the conditions that are associated with Chest pain:

Chest pain (4,888 conditions)

Related publications that referenced our studies

Pang, T., & Gudi, A., "Chest pain following the use of fluvoxamine in depression", Proceedings of Singapore Healthcare, 2018 Jan .
Pang, T., & Gudi, A., "Chest pain following the use of fluvoxamine in depression", Proceedings of Singapore Healthcare, 2018 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on ethinyl estradiol; norgestimate (the active ingredients of Tri-sprintec) and Tri-sprintec (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.