Trintellix and C. diff - a phase IV clinical study of FDA data

Summary:

C. diff is reported as a side effect among people who take Trintellix (vortioxetine hydrobromide), especially for people who are male, 50-59 old, also take Potassium Chloride, and have Multiple sclerosis.

The phase IV clinical study analyzes which people have C. diff when taking Trintellix. It is created by eHealthMe based on reports of 12,454 people who have side effects when taking Trintellix from the FDA, and is updated regularly.

What is Trintellix?

Trintellix has active ingredients of vortioxetine hydrobromide. It is often used in depression. eHealthMe is studying from 13,064 Trintellix users. Check the latest studies of Trintellix.

What is C. diff?

C. diff is found to be associated with 1,642 drugs and 1,767 conditions by eHealthMe. Check the latest studies of C. diff.

On Oct, 24, 2025

12,454 people reported to have side effects when taking Trintellix.
Among them, 13 people (0.1%) have C. diff.

Among these 13 people:

What is the gender of people who have C. diff when taking Trintellix? *

female: 38.46 %
male: 61.54 %

What is the age of people who have C. diff when taking Trintellix? *

What are other drugs people take besides Trintellix? *

What are other side effects people have besides C. diff? *

Urinary Tract Infection: 6 people, 46.15%
Kidney Stones: 6 people, 46.15%
Weakness: 4 people, 30.77%
Urosepsis (secondary infection that occurs when a urinary tract infection spreads to the bloodstream): 4 people, 30.77%
Feeding Disorder (when children refuse to eat certain food groups): 4 people, 30.77%
Fall: 4 people, 30.77%
Pharyngitis Streptococcal (inflammation of the pharynx caused by infection from. streptococcus): 4 people, 30.77%
Diarrhea: 4 people, 30.77%
Gastrointestinal Disorder (functional problems of gastrointestinal tract): 4 people, 30.77%
Systemic Lupus Erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue): 4 people, 30.77%

What are the existing conditions these people have? *

Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 8 people, 61.54%
Urinary Tract Infection: 4 people, 30.77%
Tremor (trembling or shaking movements in one or more parts of your body): 4 people, 30.77%
Back Pain: 4 people, 30.77%
Bladder Spasm: 4 people, 30.77%
Carotid Artery Disease: 4 people, 30.77%
Constipation: 4 people, 30.77%
Fever: 4 people, 30.77%
Gout (uric acid crystals building up in the body): 4 people, 30.77%
High Blood Pressure: 4 people, 30.77%

* Approximation only. Some reports may have incomplete information.

Do you take Trintellix and have C. diff?

- Check whether C. diff is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Trintellix:

Trintellix (13,064 reports)

C. diff treatments and more:

C. diff (13,844 reports)

Browse all side effects of Trintellix:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with C. diff:

C. diff (1,642 drugs)

Browse all the conditions that are associated with C. diff:

C. diff (1,767 conditions)

Drugs similar to Trintellix and C. diff :

How the study uses the data?

The study uses data from the FDA. It is based on vortioxetine hydrobromide (the active ingredients of Trintellix) and Trintellix (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.