Lexapro and C. diff - a phase IV clinical study of FDA data

Summary:

C. diff is reported as a side effect among people who take Lexapro (escitalopram oxalate), especially for people who are female, 50-59 old, have been taking the drug for 1 - 6 months also take Ativan, and have Multiple myeloma.

The phase IV clinical study analyzes which people have C. diff when taking Lexapro. It is created by eHealthMe based on reports of 82,231 people who have side effects when taking Lexapro from the FDA, and is updated regularly.

What is Lexapro?

Lexapro has active ingredients of escitalopram oxalate. It is often used in depression. eHealthMe is studying from 91,444 Lexapro users. Check the latest studies of Lexapro.

What is C. diff?

C. diff is found to be associated with 1,642 drugs and 1,766 conditions by eHealthMe. Check the latest studies of C. diff.

On Sep, 10, 2025

82,231 people reported to have side effects when taking Lexapro.
Among them, 139 people (0.17%) have C. diff.

Among these 139 people:

How long have people been on Lexapro when they have C. diff? *

What is the gender of people who have C. diff when taking Lexapro? *

female: 61.76 %
male: 38.24 %

What is the age of people who have C. diff when taking Lexapro? *

What are other drugs people take besides Lexapro? *

What are other side effects people have besides C. diff? *

Fatigue (feeling of tiredness): 46 people, 33.09%
Pain: 45 people, 32.37%
Pneumonia: 44 people, 31.65%
Dyspnea (difficult or laboured breathing): 43 people, 30.94%
Headache (pain in head): 41 people, 29.50%
Anaemia (lack of blood): 39 people, 28.06%
Chest Pain: 38 people, 27.34%
Dehydration (dryness resulting from the removal of water): 38 people, 27.34%
Abdominal Pain: 36 people, 25.90%
Osteomyelitis (infection of bone): 31 people, 22.30%

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 21 people, 15.11%
High Blood Pressure: 13 people, 9.35%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 12 people, 8.63%
Nausea (feeling of having an urge to vomit): 7 people, 5.04%
Pain: 6 people, 4.32%
Diabetes: 6 people, 4.32%
Fatigue (feeling of tiredness): 6 people, 4.32%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 3.60%
Metastases To Bone (cancer spreads to bone): 5 people, 3.60%
Sleep Disorder: 5 people, 3.60%

* Approximation only. Some reports may have incomplete information.

Do you take Lexapro and have C. diff?

- Check whether C. diff is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Lexapro:

Lexapro (91,444 reports)

C. diff treatments and more:

C. diff (13,844 reports)

Common Lexapro side effects:

Browse all side effects of Lexapro:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Common drugs associated with C. diff:

Browse all the drugs that are associated with C. diff:

C. diff (1,642 drugs)

Common conditions associated with C. diff:

Plasmacytoma of bone: 814 reports
Hypertension: 750 reports
Acute lymphocytic leukemia (all): 516 reports
Alternative medicine - pain relief: 482 reports
Regional enteritis: 454 reports
Urinary tract infection: 411 reports
Multiple sclerosis: 348 reports
Colitis ulcerative: 343 reports
Ra: 332 reports
Osteoporosis: 322 reports

Browse all the conditions that are associated with C. diff:

C. diff (1,766 conditions)

Drugs similar to Lexapro and C. diff :

Related publications that referenced our studies

O’Brien FE, O’Connor RM, Clarke G, Donovan MD, Dinan TG, Griffin BT, Cryan JF, "The P-glycoprotein inhibitor cyclosporin A differentially influences behavioural and neurochemical responses to the antidepressant escitalopram", Behavioural brain research, 2014 Mar .
O’Brien FE, O’Connor RM, Clarke G, Donovan MD, Dinan TG, Griffin BT, Cryan JF, "The P-glycoprotein inhibitor cyclosporin A differentially influences behavioural and neurochemical responses to the antidepressant escitalopram", Behavioural brain research, 2014 Mar .

How the study uses the data?

The study uses data from the FDA. It is based on escitalopram oxalate (the active ingredients of Lexapro) and Lexapro (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.