Omeprazole and C. diff - a phase IV clinical study of FDA data

Summary:

C. diff is reported as a side effect among people who take Omeprazole (omeprazole), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Vancomycin, and have Pain.

The phase IV clinical study analyzes which people have C. diff when taking Omeprazole. It is created by eHealthMe based on reports of 400,982 people who have side effects when taking Omeprazole from the FDA, and is updated regularly.

What is Omeprazole?

Omeprazole has active ingredients of omeprazole. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 410,610 Omeprazole users. Check the latest studies of Omeprazole.

What is C. diff?

C. diff is found to be associated with 1,625 drugs and 1,768 conditions by eHealthMe. Check the latest studies of C. diff.

On Nov, 21, 2025

400,982 people reported to have side effects when taking Omeprazole.
Among them, 637 people (0.16%) have C. diff.

Among these 637 people:

* Approximation only. Some reports may have incomplete information.

Do you take Omeprazole and have C. diff?

- Check whether C. diff is associated with a drug or a condition (FREE)
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Omeprazole:

Omeprazole (410,610 reports)

C. diff treatments and more:

C. diff (13,844 reports)

How severe was C. diff and when was it recovered:

C. diff in Omeprazole

Expand to all the drugs that have ingredients of omeprazole:

C. diff and drugs with ingredients of omeprazole (816 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Common Omeprazole side effects:

Browse all side effects of Omeprazole:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Common drugs associated with C. diff:

Browse all the drugs that are associated with C. diff:

C. diff (1,625 drugs)

Common conditions associated with C. diff:

Multiple myeloma: 814 reports
Hbp: 750 reports
Acute lymphocytic leukemia: 516 reports
Pain relief: 482 reports
Crohn's disease: 454 reports
Cystitis: 411 reports
Ms: 348 reports
Inflammatory bowel disease - ulcerative colitis: 343 reports
Ra: 332 reports
Osteoporosis: 322 reports

Browse all the conditions that are associated with C. diff:

C. diff (1,768 conditions)

Drugs similar to Omeprazole and C. diff :

How the study uses the data?

The study uses data from the FDA. It is based on omeprazole (the active ingredients of Omeprazole) and Omeprazole (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.