Tropicamide and Headache - a phase IV clinical study of FDA data

Summary:

Headache is reported as a side effect among people who take Tropicamide (tropicamide), especially for people who are female, 40-49 old, have been taking the drug for < 1 month also take Fragmin, and have Oligodendroglioma.

The phase IV clinical study analyzes which people have Headache when taking Tropicamide. It is created by eHealthMe based on reports of 1,522 people who have side effects when taking Tropicamide from the FDA, and is updated regularly.

What is Tropicamide?

Tropicamide has active ingredients of tropicamide. eHealthMe is studying from 1,529 Tropicamide users. Check the latest studies of Tropicamide.

What is Headache?

Headache (pain in head) is found to be associated with 3,756 drugs and 5,776 conditions by eHealthMe. Check the latest studies of Headache.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Sep, 01, 2026

1,522 people reported to have side effects when taking Tropicamide.
Among them, 82 people (5.39%) have Headache.

Could Tropicamide cause Headache?

Among these 82 people:

How long have people been on Tropicamide when they have Headache? *

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Headache when taking Tropicamide? *

  • female: 56.25 %
  • male: 43.75 %

What is the age of people who have Headache when taking Tropicamide? *

  • 0-1: 0.0 %
  • 2-9: 4.84 %
  • 10-19: 3.23 %
  • 20-29: 3.23 %
  • 30-39: 4.84 %
  • 40-49: 46.77 %
  • 50-59: 14.52 %
  • 60+: 22.58 %

What are other drugs people take besides Tropicamide? *

  1. Fragmin: 26 people, 31.71%
  2. Avastin: 23 people, 28.05%
  3. Dilantin: 21 people, 25.61%
  4. Methadose: 21 people, 25.61%
  5. Topiramate: 19 people, 23.17%
  6. Dexamethasone: 19 people, 23.17%
  7. Morphine Sulfate: 18 people, 21.95%
  8. Mirtazapine: 18 people, 21.95%
  9. Lorazepam: 18 people, 21.95%
  10. Levetiracetam: 18 people, 21.95%

What are other side effects people have besides Headache? *

  1. Confusional State: 32 people, 39.02%
  2. Haemorrhage (bleeding): 31 people, 37.80%
  3. High Blood Pressure: 31 people, 37.80%
  4. Weight Decreased: 31 people, 37.80%
  5. Nervous System Disorder (a general class of medical conditions affecting the nervous system): 31 people, 37.80%
  6. Weight Increased: 30 people, 36.59%
  7. Rectal Haemorrhage (bleeding from anus): 30 people, 36.59%
  8. Blood Pressure Diastolic Increased: 30 people, 36.59%
  9. Body Temperature Decreased: 30 people, 36.59%
  10. Bone Marrow Disorder: 30 people, 36.59%

What are the existing conditions these people have? *

  1. Oligodendroglioma (a type of glioma that are believed to originate from the oligodendrocytes of the brain or from a glial precursor cell): 30 people, 36.59%
  2. Brain Cancer Metastatic: 5 people, 6.10%
  3. Mydriasis (a dilation of the pupil): 5 people, 6.10%
  4. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 4 people, 4.88%
  5. Choroidal Neovascularisation (creation of new blood vessels in vascular layer of eye): 3 people, 3.66%
  6. Cystoid Macular Oedema (fluid accumulation after cataract surgery): 3 people, 3.66%
  7. Retinal Vessel Occlusion (a blockage in one of the small arteries): 3 people, 3.66%
  8. Presumed Ocular Histoplasmosis Syndrome (syndrome affecting the eye): 3 people, 3.66%
  9. Vitreous Adhesions: 2 people, 2.44%
  10. Macular Fibrosis (a thin sheet of scar tissue forms on top of the macula, in response to damage or injury): 2 people, 2.44%

* Approximation only. Some reports may have incomplete information.

Do you take Tropicamide and have Headache?

- Check whether Headache is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Tropicamide:

Headache treatments and more:

How severe was Headache and when was it recovered:

Expand to all the drugs that have ingredients of tropicamide:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Tropicamide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Headache:

Browse all the conditions that are associated with Headache:


How the study uses the data?

The study uses data from the FDA. It is based on tropicamide (the active ingredients of Tropicamide) and Tropicamide (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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