Trulicity and Ear discomfort - a phase IV clinical study of FDA data

Summary:

Ear discomfort is reported as a side effect among people who take Trulicity (dulaglutide), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Metformin, and have Type 2 diabetes.

The phase IV clinical study analyzes which people have Ear discomfort when taking Trulicity. It is created by eHealthMe based on reports of 76,923 people who have side effects when taking Trulicity from the FDA, and is updated regularly.

What is Trulicity?

Trulicity has active ingredients of dulaglutide. It is often used in weight loss. eHealthMe is studying from 77,529 Trulicity users. Check the latest studies of Trulicity.

What is Ear discomfort?

Ear discomfort is found to be associated with 831 drugs and 1,349 conditions by eHealthMe. Check the latest studies of Ear discomfort.



On Jul, 10, 2026

76,923 people reported to have side effects when taking Trulicity.
Among them, 26 people (0.03%) have Ear discomfort.

Could Trulicity cause Ear discomfort?

Among these 26 people:

How long have people been on Trulicity when they have Ear discomfort? *

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Ear discomfort when taking Trulicity? *

  • female: 80 %
  • male: 20 %

What is the age of people who have Ear discomfort when taking Trulicity? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 6.67 %
  • 50-59: 46.67 %
  • 60+: 46.67 %

What are other drugs people take besides Trulicity? *

  1. Metformin: 8 people, 30.77%
  2. Dupixent: 5 people, 19.23%
  3. Tylenol: 5 people, 19.23%
  4. Calcium: 4 people, 15.38%
  5. Gabapentin: 4 people, 15.38%
  6. Albuterol Sulfate: 3 people, 11.54%
  7. Vitamin D3: 3 people, 11.54%
  8. Humira: 3 people, 11.54%
  9. Singulair: 3 people, 11.54%
  10. Zyrtec: 2 people, 7.69%

What are other side effects people have besides Ear discomfort? *

  1. Fatigue (feeling of tiredness): 6 people, 23.08%
  2. Weakness: 5 people, 19.23%
  3. Visual Impairment: 5 people, 19.23%
  4. Nasopharyngitis (inflammation of the nasopharynx): 5 people, 19.23%
  5. Cough: 4 people, 15.38%
  6. Ocular Discomfort (a generic expression when there is lack of ease in/about the eyes): 4 people, 15.38%
  7. Back Pain: 4 people, 15.38%
  8. Dizziness: 4 people, 15.38%
  9. Joint Pain: 3 people, 11.54%
  10. Nausea (feeling of having an urge to vomit): 3 people, 11.54%

What are the existing conditions these people have? *

  1. Type 2 Diabetes: 6 people, 23.08%
  2. Ankylosing Spondylitis (type of arthritis affecting the spine): 3 people, 11.54%
  3. Asthma: 3 people, 11.54%
  4. Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 3 people, 11.54%
  5. Nasal Polyps (masses that develop in the lining of the nose): 3 people, 11.54%
  6. Diabetes: 2 people, 7.69%
  7. Wheezing (a high-pitched whistling sound made while you breath): 1 person, 3.85%
  8. Hypersensitivity: 1 person, 3.85%
  9. Blood Glucose Abnormal: 1 person, 3.85%
  10. Cardiac Failure: 1 person, 3.85%

* Approximation only. Some reports may have incomplete information.

Do you take Trulicity and have Ear discomfort?

- Check whether Ear discomfort is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Trulicity:

Ear discomfort treatments and more:

How severe was Ear discomfort and when was it recovered:

Expand to all the drugs that have ingredients of dulaglutide:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Trulicity:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Ear discomfort:

Browse all the conditions that are associated with Ear discomfort:


How the study uses the data?

The study uses data from the FDA. It is based on dulaglutide (the active ingredients of Trulicity) and Trulicity (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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