Trulicity and Ejection fraction decreased - a phase IV clinical study of FDA data

Summary:

Ejection fraction decreased is reported as a side effect among people who take Trulicity (dulaglutide), especially for people who are 60+ old, have been taking the drug for 1 - 6 months also take Entresto, and have Type 2 diabetes.

The phase IV clinical study analyzes which people have Ejection fraction decreased when taking Trulicity. It is created by eHealthMe based on reports of 76,923 people who have side effects when taking Trulicity from the FDA, and is updated regularly.

What is Trulicity?

Trulicity has active ingredients of dulaglutide. It is often used in weight loss. eHealthMe is studying from 77,529 Trulicity users. Check the latest studies of Trulicity.

What is Ejection fraction decreased?

Ejection fraction decreased (systolic heart failure) is found to be associated with 1,060 drugs and 1,256 conditions by eHealthMe. Check the latest studies of Ejection fraction decreased.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 20, 2026

76,923 people reported to have side effects when taking Trulicity.
Among them, 20 people (0.03%) have Ejection fraction decreased.

$Could Trulicity cause Ejection fraction decreased?$

Among these 20 people:

How long have people been on Trulicity when they have Ejection fraction decreased? *

What is the age of people who have Ejection fraction decreased when taking Trulicity? *

What are other drugs people take besides Trulicity? *

What are other side effects people have besides Ejection fraction decreased? *

Fatigue (feeling of tiredness): 9 people, 45.00%
Dyspnea (difficult or laboured breathing): 7 people, 35.00%
Hypotension (abnormally low blood pressure): 7 people, 35.00%
Blood Glucose Increased: 6 people, 30.00%
Cough: 4 people, 20.00%
Nausea (feeling of having an urge to vomit): 4 people, 20.00%
Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 3 people, 15.00%
Weight Increased: 3 people, 15.00%
Stress And Anxiety: 3 people, 15.00%
Cardiac Failure: 3 people, 15.00%

What are the existing conditions these people have? *

Type 2 Diabetes: 4 people, 20.00%
Stress And Anxiety: 2 people, 10.00%
Rhinitis (a medical term for irritation and inflammation of the mucous membrane inside the nose): 2 people, 10.00%
Left Ventricular Failure (left ventricle fails to contract forcefully): 2 people, 10.00%
Heart Rate Irregular: 2 people, 10.00%
Diabetes: 2 people, 10.00%
Coronary Heart Disease (narrowing or blockage of the coronary arteries): 2 people, 10.00%
Constipation: 2 people, 10.00%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 2 people, 10.00%
Wheezing (a high-pitched whistling sound made while you breath): 1 person, 5.00%

* Approximation only. Some reports may have incomplete information.

Do you take Trulicity and have Ejection fraction decreased?

- Check whether Ejection fraction decreased is associated with a drug or a condition
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Trulicity:

Trulicity (77,529 reports)

Browse all side effects of Trulicity:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Ejection fraction decreased:

Ejection fraction decreased (1,060 drugs)

Browse all the conditions that are associated with Ejection fraction decreased:

Ejection fraction decreased (1,256 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on dulaglutide (the active ingredients of Trulicity) and Trulicity (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.