Trulicity and Hiatal hernia - a phase IV clinical study of FDA data

Summary:

Hiatal hernia is reported as a side effect among people who take Trulicity (dulaglutide), especially for people who are female, 60+ old, also take Otezla, and have Type 2 diabetes.

The phase IV clinical study analyzes which people have Hiatal hernia when taking Trulicity. It is created by eHealthMe based on reports of 76,923 people who have side effects when taking Trulicity from the FDA, and is updated regularly.

What is Trulicity?

Trulicity has active ingredients of dulaglutide. It is often used in weight loss. eHealthMe is studying from 77,529 Trulicity users. Check the latest studies of Trulicity.

What is Hiatal hernia?

Hiatal hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm) is found to be associated with 1,305 drugs and 1,564 conditions by eHealthMe. Check the latest studies of Hiatal hernia.

On Jul, 04, 2026

76,923 people reported to have side effects when taking Trulicity.
Among them, 24 people (0.03%) have Hiatal hernia.

Among these 24 people:

What is the gender of people who have Hiatal hernia when taking Trulicity? *

female: 72.73 %
male: 27.27 %

What is the age of people who have Hiatal hernia when taking Trulicity? *

What are other drugs people take besides Trulicity? *

Otezla: 4 people, 16.67%
Zofran: 3 people, 12.50%
Cymbalta: 3 people, 12.50%
Zithromax: 3 people, 12.50%
Imitrex: 3 people, 12.50%
Hydroxyzine Hydrochloride: 3 people, 12.50%
Hydroxyurea: 3 people, 12.50%
Finasteride: 3 people, 12.50%
Famotidine: 3 people, 12.50%
Dulera: 3 people, 12.50%

What are other side effects people have besides Hiatal hernia? *

Nausea (feeling of having an urge to vomit): 6 people, 25.00%
Dizziness: 6 people, 25.00%
Abdominal Distension: 5 people, 20.83%
Oropharyngeal Pain: 5 people, 20.83%
Pain: 5 people, 20.83%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 20.83%
Nausea And Vomiting: 5 people, 20.83%
Diarrhea: 5 people, 20.83%
Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 4 people, 16.67%
Weight Decreased: 4 people, 16.67%

What are the existing conditions these people have? *

Type 2 Diabetes: 12 people, 50.00%
Psoriasis (immune-mediated disease that affects the skin): 4 people, 16.67%
Essential Thrombocythaemia (chronic blood cancer): 3 people, 12.50%
Hidradenitis (chronic disease of a type of sweat gland): 3 people, 12.50%
Weight Increased: 2 people, 8.33%
Depression: 2 people, 8.33%
Fibromyalgia (a long-term condition which causes pain all over the body): 2 people, 8.33%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 8.33%
High Blood Cholesterol: 2 people, 8.33%
Itching: 2 people, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Trulicity and have Hiatal hernia?

- Check whether Hiatal hernia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Trulicity:

Trulicity (77,529 reports)

Hiatal hernia treatments and more:

Hiatal hernia (28,705 reports)

Browse all side effects of Trulicity:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hiatal hernia:

Hiatal hernia (1,305 drugs)

Browse all the conditions that are associated with Hiatal hernia:

Hiatal hernia (1,564 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on dulaglutide (the active ingredients of Trulicity) and Trulicity (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.