Trulicity and Hypothyroidism - a phase IV clinical study of FDA data

Summary:

Hypothyroidism is reported as a side effect among people who take Trulicity (dulaglutide), especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months also take Jardiance, and have Type 2 diabetes.

The phase IV clinical study analyzes which people have Hypothyroidism when taking Trulicity. It is created by eHealthMe based on reports of 76,923 people who have side effects when taking Trulicity from the FDA, and is updated regularly.

What is Trulicity?

Trulicity has active ingredients of dulaglutide. It is often used in weight loss. eHealthMe is studying from 77,529 Trulicity users. Check the latest studies of Trulicity.

What is Hypothyroidism?

Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development) is found to be associated with 1,616 drugs and 2,600 conditions by eHealthMe. Check the latest studies of Hypothyroidism.

On Jul, 22, 2026

76,923 people reported to have side effects when taking Trulicity.
Among them, 46 people (0.06%) have Hypothyroidism.

Among these 46 people:

How long have people been on Trulicity when they have Hypothyroidism? *

What is the gender of people who have Hypothyroidism when taking Trulicity? *

female: 64.1 %
male: 35.9 %

What is the age of people who have Hypothyroidism when taking Trulicity? *

What are other drugs people take besides Trulicity? *

What are other side effects people have besides Hypothyroidism? *

Nausea (feeling of having an urge to vomit): 11 people, 23.91%
Weight Increased: 8 people, 17.39%
Mood Swings (an extreme or rapid change in mood): 7 people, 15.22%
Heart Palpitations (feelings or sensations that your heart is pounding or racing): 7 people, 15.22%
Nausea And Vomiting: 7 people, 15.22%
Fatigue (feeling of tiredness): 7 people, 15.22%
Dizziness: 7 people, 15.22%
Diarrhea: 7 people, 15.22%
Blood Glucose Decreased: 7 people, 15.22%
Blood Glucose Increased: 6 people, 13.04%

What are the existing conditions these people have? *

Type 2 Diabetes: 8 people, 17.39%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 7 people, 15.22%
Cushing's Syndrome (obesity, a rounded face, increased fat): 6 people, 13.04%
Diabetes: 6 people, 13.04%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 5 people, 10.87%
Hepatocellular Carcinoma (liver cancer): 3 people, 6.52%
Drowsiness: 3 people, 6.52%
High Blood Cholesterol: 3 people, 6.52%
Hyperuricaemia (level of uric acid in the blood that is abnormally high): 2 people, 4.35%
Hyperlipidaemia (presence of excess lipids in the blood): 2 people, 4.35%

* Approximation only. Some reports may have incomplete information.

Do you take Trulicity and have Hypothyroidism?

- Check whether Hypothyroidism is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Trulicity:

Trulicity (77,529 reports)

Hypothyroidism treatments and more:

Hypothyroidism (168,065 reports)

Browse all side effects of Trulicity:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hypothyroidism:

Hypothyroidism (1,616 drugs)

Browse all the conditions that are associated with Hypothyroidism:

Hypothyroidism (2,600 conditions)

Related publications that referenced our studies

Ezeji GC, Inoue T, Bahtiyar G, Sacerdote A, "Hallucinations associated with miglitol use in a patient with chronic kidney disease and hypothyroidism", BMJ case reports, 2015 Feb .
Ezeji GC, Inoue T, Bahtiyar G, Sacerdote A, "Hallucinations associated with miglitol use in a patient with chronic kidney disease and hypothyroidism", BMJ case reports, 2015 Feb .

How the study uses the data?

The study uses data from the FDA. It is based on dulaglutide (the active ingredients of Trulicity) and Trulicity (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.