Trulicity and Sciatica - a phase IV clinical study of FDA data

Summary:

Sciatica is reported as a side effect among people who take Trulicity (dulaglutide), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Metformin, and have Type 2 diabetes.

The phase IV clinical study analyzes which people have Sciatica when taking Trulicity. It is created by eHealthMe based on reports of 76,923 people who have side effects when taking Trulicity from the FDA, and is updated regularly.

What is Trulicity?

Trulicity has active ingredients of dulaglutide. It is often used in weight loss. eHealthMe is studying from 77,527 Trulicity users. Check the latest studies of Trulicity.

What is Sciatica?

Sciatica (a set of symptoms including pain caused by general compression or irritation of one of five spinal nerve roots of each sciatic nerve) is found to be associated with 1,149 drugs and 1,415 conditions by eHealthMe. Check the latest studies of Sciatica.

On Oct, 27, 2025

76,923 people reported to have side effects when taking Trulicity.
Among them, 50 people (0.07%) have Sciatica.

Among these 50 people:

How long have people been on Trulicity when they have Sciatica? *

What is the gender of people who have Sciatica when taking Trulicity? *

female: 74.47 %
male: 25.53 %

What is the age of people who have Sciatica when taking Trulicity? *

What are other drugs people take besides Trulicity? *

What are other side effects people have besides Sciatica? *

Blood Glucose Increased: 12 people, 24.00%
Back Pain: 12 people, 24.00%
Nausea (feeling of having an urge to vomit): 11 people, 22.00%
Fatigue (feeling of tiredness): 10 people, 20.00%
Gait Disturbance: 9 people, 18.00%
Pain In Extremity: 7 people, 14.00%
Muscle Spasms (muscle contraction): 7 people, 14.00%
Memory Loss: 7 people, 14.00%
Joint Pain: 7 people, 14.00%
Drug Ineffective: 7 people, 14.00%

What are the existing conditions these people have? *

Type 2 Diabetes: 16 people, 32.00%
Diabetes: 14 people, 28.00%
Muscle Spasms (muscle contraction): 5 people, 10.00%
Malignant Peritoneal Neoplasm (cancer tumour of peritoneum): 4 people, 8.00%
Fibromyalgia (a long-term condition which causes pain all over the body): 3 people, 6.00%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 3 people, 6.00%
Nausea (feeling of having an urge to vomit): 2 people, 4.00%
Cushing's Syndrome (obesity, a rounded face, increased fat): 2 people, 4.00%
Dizziness: 2 people, 4.00%
Gait Disturbance: 2 people, 4.00%

* Approximation only. Some reports may have incomplete information.

Do you take Trulicity and have Sciatica?

- Check whether Sciatica is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Trulicity:

Trulicity (77,527 reports)

Sciatica treatments and more:

Sciatica (28,503 reports)

Browse all side effects of Trulicity:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Sciatica:

Sciatica (1,149 drugs)

Browse all the conditions that are associated with Sciatica:

Sciatica (1,415 conditions)

Drugs similar to Trulicity and Sciatica :

How the study uses the data?

The study uses data from the FDA. It is based on dulaglutide (the active ingredients of Trulicity) and Trulicity (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.