Truvada and Injection site swelling - a phase IV clinical study of FDA data

Summary:

Injection site swelling is reported as a side effect among people who take Truvada (emtricitabine; tenofovir disoproxil fumarate), especially for people who are male, 50-59 old, also take Egrifta, and have Lipodystrophy acquired.

The phase IV clinical study analyzes which people have Injection site swelling when taking Truvada. It is created by eHealthMe based on reports of 75,548 people who have side effects when taking Truvada from the FDA, and is updated regularly.

What is Truvada?

Truvada has active ingredients of emtricitabine; tenofovir disoproxil fumarate. It is often used in hiv infection. eHealthMe is studying from 76,246 Truvada users. Check the latest studies of Truvada.

What is Injection site swelling?

Injection site swelling is found to be associated with 1,057 drugs and 1,115 conditions by eHealthMe. Check the latest studies of Injection site swelling.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 30, 2026

75,548 people reported to have side effects when taking Truvada.
Among them, 14 people (0.02%) have Injection site swelling.

Could Truvada cause Injection site swelling?

Among these 14 people:

What is the gender of people who have Injection site swelling when taking Truvada? *

female: 11.11 %
male: 88.89 %

What is the age of people who have Injection site swelling when taking Truvada? *

What are other drugs people take besides Truvada? *

What are other side effects people have besides Injection site swelling? *

Injection Site Pain: 4 people, 28.57%
Injection Site Erythema (redness at injection site): 4 people, 28.57%
Muscle Aches (muscle pain): 3 people, 21.43%
Injection Site Pruritus (severe itching at injection site): 3 people, 21.43%
Injection Site Urticaria (rash of round, red welts on the skin at injection site): 3 people, 21.43%
Depression: 3 people, 21.43%
Insomnia (sleeplessness): 3 people, 21.43%
Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 3 people, 21.43%
Injection Site Discomfort: 3 people, 21.43%
Nervous System Disorder (a general class of medical conditions affecting the nervous system): 2 people, 14.29%

What are the existing conditions these people have? *

Psoriasis (immune-mediated disease that affects the skin): 2 people, 14.29%
Lipohypertrophy (a lump under the skin caused by accumulation of extra fat at the site of many subcutaneous injections of insulin): 2 people, 14.29%
Lipodystrophy Acquired (a regional loss of subcutaneous adipose tissue which usually starts in the face, extends downward acquired): 2 people, 14.29%
Tuberculosis (a bacterial infection by mycobacterium tuberculosis): 1 person, 7.14%
Stress And Anxiety: 1 person, 7.14%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 7.14%
Pain: 1 person, 7.14%
Migraine (headache): 1 person, 7.14%
Insomnia (sleeplessness): 1 person, 7.14%
High Blood Cholesterol: 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

Do you take Truvada and have Injection site swelling?

- Check whether Injection site swelling is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Truvada:

Truvada (76,246 reports)

Injection site swelling treatments and more:

Injection site swelling (69,692 reports)

How severe was Injection site swelling and when was it recovered:

Injection site swelling in Truvada

Expand to all the drugs that have ingredients of emtricitabine; tenofovir disoproxil fumarate:

Injection site swelling and drugs with ingredients of emtricitabine; tenofovir disoproxil fumarate

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Truvada:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Injection site swelling:

Injection site swelling (1,057 drugs)

Browse all the conditions that are associated with Injection site swelling:

Injection site swelling (1,115 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on emtricitabine; tenofovir disoproxil fumarate (the active ingredients of Truvada) and Truvada (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.