Truxima and Systemic lupus erythematosus - a phase IV clinical study of FDA data

Summary:

Systemic lupus erythematosus is reported as a side effect among people who take Truxima (rituximab-abbs), especially for people who are female, 40-49 old, have been taking the drug for 6 - 12 months also take Prednisone, and have Rheumatoid arthritis.

The phase IV clinical study analyzes which people have Systemic lupus erythematosus when taking Truxima. It is created by eHealthMe based on reports of 4,063 people who have side effects when taking Truxima from the FDA, and is updated regularly.

What is Truxima?

Truxima has active ingredients of rituximab-abbs. eHealthMe is studying from 4,063 Truxima users. Check the latest studies of Truxima.

What is Systemic lupus erythematosus?

Systemic lupus erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue) is found to be associated with 1,089 drugs and 1,642 conditions by eHealthMe. Check the latest studies of Systemic lupus erythematosus.

On Jul, 15, 2026

4,063 people reported to have side effects when taking Truxima.
Among them, 93 people (2.29%) have Systemic lupus erythematosus.

Could Truxima cause Systemic lupus erythematosus?

Among these 93 people:

How long have people been on Truxima when they have Systemic lupus erythematosus? *

What is the gender of people who have Systemic lupus erythematosus when taking Truxima? *

female: 100 %
male: 0.0 %

What is the age of people who have Systemic lupus erythematosus when taking Truxima? *

What are other drugs people take besides Truxima? *

Prednisone: 45 people, 48.39%
Folic Acid: 40 people, 43.01%
Enbrel: 39 people, 41.94%
Pseudoephedrine Hydrochloride: 39 people, 41.94%
Simponi: 39 people, 41.94%
Xeljanz: 39 people, 41.94%
Arava: 39 people, 41.94%
Sulfasalazine: 39 people, 41.94%
Cimzia: 39 people, 41.94%
Remicade: 39 people, 41.94%

What are other side effects people have besides Systemic lupus erythematosus? *

Swelling: 39 people, 41.94%
Arthropathy: 37 people, 39.78%
Pericarditis (inflammation of the pericardium): 37 people, 39.78%
Anti-Cyclic Citrullinated Peptide Antibody Positive: 36 people, 38.71%
Drug Intolerance (drug sensitivity): 36 people, 38.71%
Duodenal Ulcer Perforation (untreated ulcer can burn through the wall of the stomach): 36 people, 38.71%
Glossodynia (a burning or painful sensation in the tongue): 36 people, 38.71%
Synovitis (inflammation of the synovial membrane): 36 people, 38.71%
Hand Deformity: 36 people, 38.71%
Pemphigus (any of several acute or chronic skin diseases characterized by groups of itching blisters): 36 people, 38.71%

What are the existing conditions these people have? *

Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 50 people, 53.76%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 23 people, 24.73%
Ankylosing Spondylitis (type of arthritis affecting the spine): 17 people, 18.28%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 17 people, 18.28%
Stress And Anxiety: 15 people, 16.13%
Psoriasis (immune-mediated disease that affects the skin): 10 people, 10.75%
Fever: 9 people, 9.68%
Pain: 8 people, 8.60%
Pemphigus (any of several acute or chronic skin diseases characterized by groups of itching blisters): 5 people, 5.38%
High Blood Pressure: 4 people, 4.30%

* Approximation only. Some reports may have incomplete information.

Do you take Truxima and have Systemic lupus erythematosus?

- Check whether Systemic lupus erythematosus is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Truxima:

Truxima (4,063 reports)

Browse all side effects of Truxima:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Systemic lupus erythematosus:

Systemic lupus erythematosus (1,089 drugs)

Browse all the conditions that are associated with Systemic lupus erythematosus:

Systemic lupus erythematosus (1,642 conditions)

Related publications that referenced our studies

Hania A, "Pyoderma Gangrenosum in a Patient With Systemic Lupus Erythematosus: Case Report", Journal of Medical Cases, 2014 Aug .
Hu P, Lu L, Hu B, Deng F, Fei WJ, "Cyclophosphamide‐Induced Hypertensive Encephalopathy in a Young Girl With Lupus", The Journal of Clinical Hypertension, 2012 Apr .
Hania A, "Pyoderma Gangrenosum in a Patient With Systemic Lupus Erythematosus: Case Report", Journal of Medical Cases, 2014 Aug .
Hu P, Lu L, Hu B, Deng F, Fei WJ, "Cyclophosphamide‐Induced Hypertensive Encephalopathy in a Young Girl With Lupus", The Journal of Clinical Hypertension, 2012 Apr .

How the study uses the data?

The study uses data from the FDA. It is based on rituximab-abbs (the active ingredients of Truxima) and Truxima (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.