Tykerb and Pancreatitis - a phase IV clinical study of FDA data
Summary:
Pancreatitis is reported as a side effect among people who take Tykerb (lapatinib ditosylate), especially for people who are female, 50-59 old, have been taking the drug for 1 - 6 months also take Xeloda, and have Brain neoplasm malignant.
The phase IV clinical study analyzes which people have Pancreatitis when taking Tykerb. It is created by eHealthMe based on reports of 12,186 people who have side effects when taking Tykerb from the FDA, and is updated regularly.
What is Tykerb?
Tykerb has active ingredients of lapatinib ditosylate. It is often used in breast cancer. eHealthMe is studying from 12,231 Tykerb users. Check the latest studies of Tykerb.
What is Pancreatitis?
Pancreatitis (inflammation of pancreas) is found to be associated with 1,766 drugs and 2,025 conditions by eHealthMe. Check the latest studies of Pancreatitis.
12,186 people reported to have side effects when taking Tykerb.
Among them, 24 people (0.2%) have Pancreatitis.

Among these 24 people:
How long have people been on Tykerb when they have Pancreatitis? *
- < 1 month: 0.0 %
- 1 - 6 months: 100 %
- 6 - 12 months: 0.0 %
- 1 - 2 years: 0.0 %
- 2 - 5 years: 0.0 %
- 5 - 10 years: 0.0 %
- 10+ years: 0.0 %
What is the gender of people who have Pancreatitis when taking Tykerb? *
- female: 100 %
- male: 0.0 %
What is the age of people who have Pancreatitis when taking Tykerb? *
- 0-1: 0.0 %
- 2-9: 0.0 %
- 10-19: 0.0 %
- 20-29: 0.0 %
- 30-39: 16.67 %
- 40-49: 8.33 %
- 50-59: 58.33 %
- 60+: 16.67 %
What are other drugs people take besides Tykerb? *
- Xeloda: 15 people, 62.50%
- Synthroid: 4 people, 16.67%
- Zoloft: 4 people, 16.67%
- Arimidex: 4 people, 16.67%
- Keppra: 3 people, 12.50%
- Lorazepam: 2 people, 8.33%
- Herceptin: 2 people, 8.33%
- Folic Acid: 2 people, 8.33%
- Megestrol Acetate: 2 people, 8.33%
- Celexa: 2 people, 8.33%
What are other side effects people have besides Pancreatitis? *
- Diarrhea: 7 people, 29.17%
- Nausea (feeling of having an urge to vomit): 7 people, 29.17%
- Depression: 3 people, 12.50%
- Fatigue (feeling of tiredness): 3 people, 12.50%
- Nausea And Vomiting: 3 people, 12.50%
- Weight Decreased: 3 people, 12.50%
- Pain: 2 people, 8.33%
- Insomnia (sleeplessness): 2 people, 8.33%
- Abdominal Pain Upper: 2 people, 8.33%
- Death: 2 people, 8.33%
What are the existing conditions these people have? *
- Neoplasm Malignant (cancer tumour): 1 person, 4.17%
- Malignant Neoplasm Of Spinal Cord (cancer tumour of spinal cord): 1 person, 4.17%
- High Blood Pressure: 1 person, 4.17%
- Breast Cancer Female: 1 person, 4.17%
- Brain Neoplasm Malignant (brain cancer tumour): 1 person, 4.17%
* Approximation only. Some reports may have incomplete information.
Do you take Tykerb and have Pancreatitis?
- Check whether Pancreatitis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, long term effects of, and alternative drugs to Tykerb:
- Tykerb (12,231 reports)
Pancreatitis treatments and more:
- Pancreatitis (62,704 reports)
How severe was Pancreatitis and when was it recovered:
Expand to all the drugs that have ingredients of lapatinib ditosylate:
Sub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Tykerb:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all the drugs that are associated with Pancreatitis:
- Pancreatitis (1,766 drugs)
Browse all the conditions that are associated with Pancreatitis:
- Pancreatitis (2,025 conditions)
Related publications that referenced our studies
- Sirkeci, ?., Sirkeci, E. E., & Ta?el, B. , "Rivaroxaban-induced acute pancreatitis", The European Research Journal, 2018 Jan .
- Liao, K. F., Huang, P. T., Lin, C. C., Lin, C. L., & Lai, S. W., "Fluvastatin use and risk of acute pancreatitis: a population-based case-control study in Taiwan", Biomedicine, 2014 Jan .
- Arshad F, Ladakhi Y, Khan MA, "A rare case of carbamazepine induced pancreatitis", International Journal of Students’ Research, 2013 Jul .
- Das S, Mondal S, Dey JK, Bandyopadhyay S, Saha I, Tripathi SK, "A case of montelukast induced hypercholesterolemia, severe hypertriglyceridemia and pancreatitis", Journal of Young Pharmacists, 2013 Jun .
- Sirkeci, ?., Sirkeci, E. E., & Ta?el, B. , "Rivaroxaban-induced acute pancreatitis", The European Research Journal, 2018 Jan .
- Liao, K. F., Huang, P. T., Lin, C. C., Lin, C. L., & Lai, S. W., "Fluvastatin use and risk of acute pancreatitis: a population-based case-control study in Taiwan", Biomedicine, 2014 Jan .
- Arshad F, Ladakhi Y, Khan MA, "A rare case of carbamazepine induced pancreatitis", International Journal of Students’ Research, 2013 Jul .
- Das S, Mondal S, Dey JK, Bandyopadhyay S, Saha I, Tripathi SK, "A case of montelukast induced hypercholesterolemia, severe hypertriglyceridemia and pancreatitis", Journal of Young Pharmacists, 2013 Jun .
How the study uses the data?
The study uses data from the FDA. It is based on lapatinib ditosylate (the active ingredients of Tykerb) and Tykerb (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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