1. Home
  2. Analysis
  3. Tylenol-w-codeine-no-3
  4. Lymphoma

Tylenol w/ codeine no. 3 and Lymphoma - a phase IV clinical study of FDA data

Summary:

Lymphoma is reported as a side effect among people who take Tylenol w/ codeine no. 3 (acetaminophen; codeine phosphate), especially for people who are male, 60+ old, also take Methotrexate, and have Eczema.

The phase IV clinical study analyzes which people have Lymphoma when taking Tylenol w/ codeine no. 3. It is created by eHealthMe based on reports of 4,453 people who have side effects when taking Tylenol w/ codeine no. 3 from the FDA, and is updated regularly.

What is Tylenol w/ codeine no. 3?

Tylenol w/ codeine no. 3 has active ingredients of acetaminophen; codeine phosphate. It is often used in pain. eHealthMe is studying from 4,920 Tylenol w/ codeine no. 3 users. Check the latest studies of Tylenol w/ codeine no. 3.

What is Lymphoma?

Lymphoma (cancer that begins in immune system cells) is found to be associated with 958 drugs and 1,013 conditions by eHealthMe. Check the latest studies of Lymphoma.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 18, 2026

4,453 people reported to have side effects when taking Tylenol w/ codeine no. 3.
Among them, 11 people (0.25%) have Lymphoma.

Could Tylenol w/ codeine no. 3 cause Lymphoma?

Among these 11 people:

What is the gender of people who have Lymphoma when taking Tylenol w/ codeine no. 3? *

  • female: 45.45 %
  • male: 54.55 %

What is the age of people who have Lymphoma when taking Tylenol w/ codeine no. 3? *

  • 0-1: 0.0 %
  • 2-9: 37.5 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 12.5 %
  • 50-59: 0.0 %
  • 60+: 50.0 %

What are other drugs people take besides Tylenol w/ codeine no. 3? *

  1. Methotrexate: 7 people, 63.64%
  2. Zofran: 4 people, 36.36%
  3. Ranitidine: 4 people, 36.36%
  4. Aldara: 4 people, 36.36%
  5. Allopurinol: 4 people, 36.36%
  6. Amoxicillin And Clavulanate Potassium: 4 people, 36.36%
  7. Cimetidine: 4 people, 36.36%
  8. Elidel: 4 people, 36.36%
  9. Fluoxetine: 4 people, 36.36%
  10. Vyvanse: 4 people, 36.36%

What are other side effects people have besides Lymphoma? *

  1. Lymph Follicular Hypertrophy (an increase in the size of the lymph node follicles): 5 people, 45.45%
  2. Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters): 4 people, 36.36%
  3. Stress And Anxiety: 4 people, 36.36%
  4. Allergic Rhinitis: 4 people, 36.36%
  5. Eczema Eyelids (patches of skin become rough and inflamed, with itching and bleeding blisters on eyelid): 4 people, 36.36%
  6. Otitis (ear infection): 3 people, 27.27%
  7. Fever: 3 people, 27.27%
  8. Hallucination, Auditory (perceiving sounds without auditory stimulus): 3 people, 27.27%
  9. Impulse-Control Disorder: 3 people, 27.27%
  10. Lung Neoplasm (tumour of lung): 3 people, 27.27%

What are the existing conditions these people have? *

  1. Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters): 4 people, 36.36%
  2. Ventricular Fibrillation (abnormally irregular heart rhythm): 1 person, 9.09%
  3. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 9.09%
  4. Restless Leg Syndrome (a powerful urge to move your legs): 1 person, 9.09%
  5. Osteoporosis (bones weak and more likely to break): 1 person, 9.09%
  6. Dementia Alzheimer's Type (loss of mental ability with alzheimer's symptom): 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Tylenol w/ codeine no. 3 and have Lymphoma?

- Check whether Lymphoma is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Tylenol w/ codeine no. 3:

Lymphoma treatments and more:

How severe was Lymphoma and when was it recovered:

Expand to all the drugs that have ingredients of acetaminophen; codeine phosphate:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Tylenol w/ codeine no. 3:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Lymphoma:

Browse all the conditions that are associated with Lymphoma:

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on acetaminophen; codeine phosphate (the active ingredients of Tylenol w/ codeine no. 3) and Tylenol w/ codeine no. 3 (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

Recent studies on eHealthMe:

© 2026 eHealthMe.com. All rights reserved. Use of this site constitutes acceptance of eHealthMe.com's terms of service and privacy policy.