Tylenol w/ codeine and Erythema multiforme - a phase IV clinical study of FDA data

Summary:

Erythema multiforme is reported as a side effect among people who take Tylenol w/ codeine (acetaminophen; codeine phosphate), especially for people who are female, 30-39 old, have been taking the drug for < 1 month also take Lamictal, and have Bipolar disorder.

The phase IV clinical study analyzes which people have Erythema multiforme when taking Tylenol w/ codeine. It is created by eHealthMe based on reports of 7,307 people who have side effects when taking Tylenol w/ codeine from the FDA, and is updated regularly.

What is Tylenol w/ codeine?

Tylenol w/ codeine has active ingredients of acetaminophen; codeine phosphate. It is often used in pain. eHealthMe is studying from 8,107 Tylenol w/ codeine users. Check the latest studies of Tylenol w/ codeine.

What is Erythema multiforme?

Erythema multiforme (a type of hypersensitivity reaction) is found to be associated with 1,708 drugs and 2,920 conditions by eHealthMe. Check the latest studies of Erythema multiforme.

On Jul, 06, 2026

7,307 people reported to have side effects when taking Tylenol w/ codeine.
Among them, 21 people (0.29%) have Erythema multiforme.

Could Tylenol w/ codeine cause Erythema multiforme?

Among these 21 people:

How long have people been on Tylenol w/ codeine when they have Erythema multiforme? *

What is the gender of people who have Erythema multiforme when taking Tylenol w/ codeine? *

female: 80.95 %
male: 19.05 %

What is the age of people who have Erythema multiforme when taking Tylenol w/ codeine? *

What are other drugs people take besides Tylenol w/ codeine? *

Lamictal: 7 people, 33.33%
Lexapro: 5 people, 23.81%
Acetaminophen: 5 people, 23.81%
Bextra: 4 people, 19.05%
Triamcinolone Acetonide: 3 people, 14.29%
Dilantin: 3 people, 14.29%
Tegretol: 3 people, 14.29%
Naprosyn: 3 people, 14.29%
Augmentin '125': 2 people, 9.52%
Levofloxacin: 2 people, 9.52%

What are other side effects people have besides Erythema multiforme? *

Mucous Membrane Disorder (disease of mucous membrane): 4 people, 19.05%
Blindness: 4 people, 19.05%
Injury: 4 people, 19.05%
Hypersensitivity: 4 people, 19.05%
Fever: 3 people, 14.29%
Vaginal Obstruction: 3 people, 14.29%
Rashes (redness): 3 people, 14.29%
Liver Function Tests Nos Abnormal: 2 people, 9.52%
Itching: 2 people, 9.52%
Hypotension (abnormally low blood pressure): 2 people, 9.52%

What are the existing conditions these people have? *

Bipolar Disorder (mood disorder): 5 people, 23.81%
Trigeminal Neuralgia (a painful condition of the nerve responsible for most facial sensation): 3 people, 14.29%
Oropharyngeal Pain: 2 people, 9.52%
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 2 people, 9.52%
Urinary Tract Pain: 1 person, 4.76%
Throat Irritation: 1 person, 4.76%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 4.76%
Pharyngolaryngeal Pain: 1 person, 4.76%
Nausea (feeling of having an urge to vomit): 1 person, 4.76%
High Blood Pressure: 1 person, 4.76%

* Approximation only. Some reports may have incomplete information.

Do you take Tylenol w/ codeine and have Erythema multiforme?

- Check whether Erythema multiforme is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Tylenol w/ codeine:

Tylenol w/ codeine (8,107 reports)

Erythema multiforme treatments and more:

Erythema multiforme (56,072 reports)

How severe was Erythema multiforme and when was it recovered:

Erythema multiforme in Tylenol w/ codeine

Expand to all the drugs that have ingredients of acetaminophen; codeine phosphate:

Erythema multiforme and drugs with ingredients of acetaminophen; codeine phosphate (254 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Tylenol w/ codeine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on acetaminophen; codeine phosphate (the active ingredients of Tylenol w/ codeine) and Tylenol w/ codeine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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