Ultracet and Delirium - a phase IV clinical study of FDA data

Summary:

Delirium is reported as a side effect among people who take Ultracet (acetaminophen; tramadol hydrochloride), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Norvasc, and have High blood pressure.

The phase IV clinical study analyzes which people have Delirium when taking Ultracet. It is created by eHealthMe based on reports of 6,139 people who have side effects when taking Ultracet from the FDA, and is updated regularly.

What is Ultracet?

Ultracet has active ingredients of acetaminophen; tramadol hydrochloride. It is often used in pain. eHealthMe is studying from 6,351 Ultracet users. Check the latest studies of Ultracet.

What is Delirium?

Delirium (wild excitement) is found to be associated with 1,466 drugs and 2,975 conditions by eHealthMe. Check the latest studies of Delirium.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 18, 2026

6,139 people reported to have side effects when taking Ultracet.
Among them, 38 people (0.62%) have Delirium.

Among these 38 people:

How long have people been on Ultracet when they have Delirium? *

What is the gender of people who have Delirium when taking Ultracet? *

female: 51.35 %
male: 48.65 %

What is the age of people who have Delirium when taking Ultracet? *

What are other drugs people take besides Ultracet? *

What are other side effects people have besides Delirium? *

Diarrhea: 13 people, 34.21%
Nausea (feeling of having an urge to vomit): 13 people, 34.21%
Pneumonia: 13 people, 34.21%
Weakness: 11 people, 28.95%
Nausea And Vomiting: 11 people, 28.95%
Insomnia (sleeplessness): 10 people, 26.32%
Gastritis (inflammation of stomach): 10 people, 26.32%
Cellulitis (infection under the skin): 10 people, 26.32%
Cough: 10 people, 26.32%
Confusional State: 10 people, 26.32%

What are the existing conditions these people have? *

High Blood Pressure: 10 people, 26.32%
Multiple Myeloma (cancer of the plasma cells): 8 people, 21.05%
Type 2 Diabetes: 6 people, 15.79%
Insomnia (sleeplessness): 6 people, 15.79%
Bone Pain: 5 people, 13.16%
Cardiac Failure Congestive: 4 people, 10.53%
Anaemia (lack of blood): 4 people, 10.53%
Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 4 people, 10.53%
Hypercalcaemia (elevated calcium (ca+) level in the blood): 4 people, 10.53%
Oedema (fluid collection in tissue): 4 people, 10.53%

* Approximation only. Some reports may have incomplete information.

Do you take Ultracet and have Delirium?

- Check whether Delirium is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Ultracet:

Ultracet (6,351 reports)

Delirium treatments and more:

Delirium (42,503 reports)

How severe was Delirium and when was it recovered:

Delirium in Ultracet

Expand to all the drugs that have ingredients of acetaminophen; tramadol hydrochloride:

Delirium and drugs with ingredients of acetaminophen; tramadol hydrochloride (56 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Ultracet:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Delirium:

Delirium (1,466 drugs)

Browse all the conditions that are associated with Delirium:

Delirium (2,975 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on acetaminophen; tramadol hydrochloride (the active ingredients of Ultracet) and Ultracet (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.