Ultram er and Acute kidney failure - a phase IV clinical study of FDA data

Summary:

Acute kidney failure is reported as a side effect among people who take Ultram er (tramadol hydrochloride), especially for people who are male, 50-59 old, have been taking the drug for 2 - 5 years also take Nexium, and have Gastroesophageal reflux disease.

The phase IV clinical study analyzes which people have Acute kidney failure when taking Ultram er. It is created by eHealthMe based on reports of 956 people who have side effects when taking Ultram er from the FDA, and is updated regularly.

What is Ultram er?

Ultram er has active ingredients of tramadol hydrochloride. It is often used in pain. eHealthMe is studying from 1,387 Ultram er users. Check the latest studies of Ultram er.

What is Acute kidney failure?

Acute kidney failure is found to be associated with 2,836 drugs and 4,493 conditions by eHealthMe. Check the latest studies of Acute kidney failure.

On Jul, 14, 2026

956 people reported to have side effects when taking Ultram er.
Among them, 21 people (2.2%) have Acute kidney failure.

Could Ultram er cause Acute kidney failure?

Among these 21 people:

How long have people been on Ultram er when they have Acute kidney failure? *

What is the gender of people who have Acute kidney failure when taking Ultram er? *

female: 47.62 %
male: 52.38 %

What is the age of people who have Acute kidney failure when taking Ultram er? *

What are other drugs people take besides Ultram er? *

What are other side effects people have besides Acute kidney failure? *

Chronic Kidney Disease: 15 people, 71.43%
Anhedonia (inability to experience pleasure from activities usually found enjoyable): 6 people, 28.57%
Emotional Distress: 6 people, 28.57%
Stress And Anxiety: 6 people, 28.57%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 23.81%
Anaemia (lack of blood): 3 people, 14.29%
Dehydration (dryness resulting from the removal of water): 3 people, 14.29%
Renal Impairment (severely reduced kidney function): 3 people, 14.29%
Hyperkalemia (damage to or disease of the kidney): 3 people, 14.29%
Gastric Ulcer (stomach ulcer): 2 people, 9.52%

What are the existing conditions these people have? *

Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 10 people, 47.62%
High Blood Pressure: 7 people, 33.33%
Hiv Infection: 6 people, 28.57%
High Blood Cholesterol: 4 people, 19.05%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 3 people, 14.29%
Osteoporosis (bones weak and more likely to break): 3 people, 14.29%
Urinary Incontinence (inability to control the flow of urine and involuntary urination): 3 people, 14.29%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 3 people, 14.29%
Hypovitaminosis (any of several diseases caused by deficiency of one or more vitamins): 3 people, 14.29%
Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 2 people, 9.52%

* Approximation only. Some reports may have incomplete information.

Do you take Ultram er and have Acute kidney failure?

- Check whether Acute kidney failure is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Ultram er:

Ultram er (1,387 reports)

Browse all side effects of Ultram er:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Acute kidney failure:

Acute kidney failure (2,836 drugs)

Browse all the conditions that are associated with Acute kidney failure:

Acute kidney failure (4,493 conditions)

Related publications that referenced our studies

Mansour HM, "Tramadol and Disseminated Intravascular Coagulopathy: A Case Report", Medicine Science, 2015 Jan .
Mansour HM, "Tramadol and Disseminated Intravascular Coagulopathy: A Case Report", Medicine Science, 2015 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on tramadol hydrochloride (the active ingredients of Ultram er) and Ultram er (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.