Ultram and Throat tightness - a phase IV clinical study of FDA data

Summary:

Throat tightness is reported as a side effect among people who take Ultram (tramadol hydrochloride), especially for people who are female, 50-59 old, have been taking the drug for < 1 month also take Xanax, and have Asthma.

The phase IV clinical study analyzes which people have Throat tightness when taking Ultram. It is created by eHealthMe based on reports of 26,802 people who have side effects when taking Ultram from the FDA, and is updated regularly.

What is Ultram?

Ultram has active ingredients of tramadol hydrochloride. It is often used in pain. eHealthMe is studying from 28,425 Ultram users. Check the latest studies of Ultram.

What is Throat tightness?

Throat tightness is found to be associated with 1,227 drugs and 1,410 conditions by eHealthMe. Check the latest studies of Throat tightness.



On Aug, 04, 2026

26,802 people reported to have side effects when taking Ultram.
Among them, 58 people (0.22%) have Throat tightness.

Could Ultram cause Throat tightness?

Among these 58 people:

How long have people been on Ultram when they have Throat tightness? *

  • < 1 month: 50 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 50 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Throat tightness when taking Ultram? *

  • female: 92.86 %
  • male: 7.14 %

What is the age of people who have Throat tightness when taking Ultram? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 2.33 %
  • 20-29: 0.0 %
  • 30-39: 11.63 %
  • 40-49: 30.23 %
  • 50-59: 32.56 %
  • 60+: 23.26 %

What are other drugs people take besides Ultram? *

  1. Lomotil: 11 people, 18.97%
  2. Altace: 11 people, 18.97%
  3. Dexilant: 11 people, 18.97%
  4. Xanax: 11 people, 18.97%
  5. Coreg: 10 people, 17.24%
  6. Valium: 10 people, 17.24%
  7. Demerol: 10 people, 17.24%
  8. Flexeril: 10 people, 17.24%
  9. Zofran: 10 people, 17.24%
  10. Xopenex Hfa: 9 people, 15.52%

What are other side effects people have besides Throat tightness? *

  1. Nausea And Vomiting: 21 people, 36.21%
  2. Dyspnea (difficult or laboured breathing): 18 people, 31.03%
  3. Rashes (redness): 15 people, 25.86%
  4. Diarrhea: 15 people, 25.86%
  5. Headache (pain in head): 14 people, 24.14%
  6. Fever: 13 people, 22.41%
  7. Drug Hypersensitivity: 13 people, 22.41%
  8. High Blood Pressure: 13 people, 22.41%
  9. Chest Pain: 12 people, 20.69%
  10. Nausea (feeling of having an urge to vomit): 11 people, 18.97%

What are the existing conditions these people have? *

  1. Renal Cell Carcinoma (a kidney cancer): 4 people, 6.90%
  2. Asthma: 4 people, 6.90%
  3. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 3 people, 5.17%
  4. Depression: 3 people, 5.17%
  5. Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 3 people, 5.17%
  6. Migraine (headache): 3 people, 5.17%
  7. Cardiac Failure: 2 people, 3.45%
  8. Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 2 people, 3.45%
  9. Nausea (feeling of having an urge to vomit): 2 people, 3.45%
  10. Hypersensitivity: 2 people, 3.45%

* Approximation only. Some reports may have incomplete information.

Do you take Ultram and have Throat tightness?

- Check whether Throat tightness is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Ultram:

Throat tightness treatments and more:

How severe was Throat tightness and when was it recovered:

Expand to all the drugs that have ingredients of tramadol hydrochloride:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Ultram:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Throat tightness:

Browse all the conditions that are associated with Throat tightness:

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on tramadol hydrochloride (the active ingredients of Ultram) and Ultram (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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