Ultram and Ventricular fibrillation - a phase IV clinical study of FDA data

Summary:

Ventricular fibrillation is reported as a side effect among people who take Ultram (tramadol hydrochloride), especially for people who are female, 50-59 old, have been taking the drug for 2 - 5 years also take Vioxx, and have High blood pressure.

The phase IV clinical study analyzes which people have Ventricular fibrillation when taking Ultram. It is created by eHealthMe based on reports of 26,802 people who have side effects when taking Ultram from the FDA, and is updated regularly.

What is Ultram?

Ultram has active ingredients of tramadol hydrochloride. It is often used in pain. eHealthMe is studying from 28,425 Ultram users. Check the latest studies of Ultram.

What is Ventricular fibrillation?

Ventricular fibrillation (abnormally irregular heart rhythm) is found to be associated with 1,099 drugs and 1,245 conditions by eHealthMe. Check the latest studies of Ventricular fibrillation.

On Jul, 05, 2026

26,802 people reported to have side effects when taking Ultram.
Among them, 69 people (0.26%) have Ventricular fibrillation.

Could Ultram cause Ventricular fibrillation?

Among these 69 people:

How long have people been on Ultram when they have Ventricular fibrillation? *

What is the gender of people who have Ventricular fibrillation when taking Ultram? *

female: 57.35 %
male: 42.65 %

What is the age of people who have Ventricular fibrillation when taking Ultram? *

What are other drugs people take besides Ultram? *

What are other side effects people have besides Ventricular fibrillation? *

Cardiac Arrest: 35 people, 50.72%
Cardiac Failure Congestive: 32 people, 46.38%
Coronary Heart Disease (narrowing or blockage of the coronary arteries): 26 people, 37.68%
Heart Attack: 25 people, 36.23%
Acute Myocardial Infarction (acute heart attack): 24 people, 34.78%
Ventricular Tachycardia (rapid heartbeat that originates in one of the lower chambers (the ventricles) of the heart): 24 people, 34.78%
High Blood Cholesterol: 22 people, 31.88%
Acute Respiratory Failure: 22 people, 31.88%
Acute Kidney Failure: 22 people, 31.88%
Urinary Tract Infection: 19 people, 27.54%

What are the existing conditions these people have? *

High Blood Pressure: 22 people, 31.88%
Sciatic Nerve Injury: 11 people, 15.94%
Pain In Extremity: 7 people, 10.14%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 4 people, 5.80%
Indigestion: 3 people, 4.35%
Insomnia (sleeplessness): 3 people, 4.35%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 3 people, 4.35%
Chest Pain: 3 people, 4.35%
Constipation: 3 people, 4.35%
Diabetes: 3 people, 4.35%

* Approximation only. Some reports may have incomplete information.

Do you take Ultram and have Ventricular fibrillation?

- Check whether Ventricular fibrillation is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Ultram:

Ultram (28,425 reports)

Browse all side effects of Ultram:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Ventricular fibrillation:

Ventricular fibrillation (1,099 drugs)

Browse all the conditions that are associated with Ventricular fibrillation:

Ventricular fibrillation (1,245 conditions)

Related publications that referenced our studies

Mansour HM, "Tramadol and Disseminated Intravascular Coagulopathy: A Case Report", Medicine Science, 2015 Jan .
Mansour HM, "Tramadol and Disseminated Intravascular Coagulopathy: A Case Report", Medicine Science, 2015 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on tramadol hydrochloride (the active ingredients of Ultram) and Ultram (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.