Unisom and Multiple myeloma - a phase IV clinical study of FDA data

Summary:

Multiple myeloma is reported as a side effect among people who take Unisom (doxylamine succinate), especially for people who are male, 60+ old, also take Elavil, and have Procedural pain.

The phase IV clinical study analyzes which people have Multiple myeloma when taking Unisom. It is created by eHealthMe based on reports of 3,362 people who have side effects when taking Unisom from the FDA, and is updated regularly.

What is Unisom?

Unisom has active ingredients of doxylamine succinate. It is often used in insomnia. eHealthMe is studying from 3,875 Unisom users. Check the latest studies of Unisom.

What is Multiple myeloma?

Multiple myeloma (cancer of the plasma cells) is found to be associated with 1,107 drugs and 1,404 conditions by eHealthMe. Check the latest studies of Multiple myeloma.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 02, 2026

3,362 people reported to have side effects when taking Unisom.
Among them, 15 people (0.45%) have Multiple myeloma.

Among these 15 people:

What is the gender of people who have Multiple myeloma when taking Unisom? *

female: 13.33 %
male: 86.67 %

What is the age of people who have Multiple myeloma when taking Unisom? *

What are other drugs people take besides Unisom? *

What are other side effects people have besides Multiple myeloma? *

Weakness: 13 people, 86.67%
Flank Pain (a distressing sensation experienced around the lower back and the upper abdomen): 13 people, 86.67%
Dyspnea (difficult or laboured breathing): 13 people, 86.67%
Ejection Fraction Decreased (systolic heart failure): 13 people, 86.67%
Electrocardiogram Qt Prolonged: 13 people, 86.67%
Electrocardiogram St Segment Depression: 13 people, 86.67%
Electrocardiogram T Wave Abnormal: 13 people, 86.67%
Encephalopathy (functioning of the brain is affected by some agent or condition): 13 people, 86.67%
Enlarged Heart: 13 people, 86.67%
Extrapyramidal Disorder (involuntary muscle spasms in the face and neck): 13 people, 86.67%

What are the existing conditions these people have? *

Swelling: 1 person, 6.67%
Procedural Pain: 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

Do you take Unisom and have Multiple myeloma?

- Check whether Multiple myeloma is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Unisom:

Unisom (3,875 reports)

Multiple myeloma treatments and more:

Multiple myeloma (516,725 reports)

Browse all side effects of Unisom:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Multiple myeloma:

Multiple myeloma (1,107 drugs)

Browse all the conditions that are associated with Multiple myeloma:

Multiple myeloma (1,404 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on doxylamine succinate (the active ingredients of Unisom) and Unisom (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.