Unithroid and Chest pain - a phase IV clinical study of FDA data

Summary:

Chest pain is reported as a side effect among people who take Unithroid (levothyroxine sodium), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Synthroid, and have High blood pressure.

The phase IV clinical study analyzes which people have Chest pain when taking Unithroid. It is created by eHealthMe based on reports of 817 people who have side effects when taking Unithroid from the FDA, and is updated regularly.

What is Unithroid?

Unithroid has active ingredients of levothyroxine sodium. It is often used in hypothyroidism. eHealthMe is studying from 890 Unithroid users. Check the latest studies of Unithroid.

What is Chest pain?

Chest pain is found to be associated with 3,458 drugs and 4,889 conditions by eHealthMe. Check the latest studies of Chest pain.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Jul, 31, 2026

817 people reported to have side effects when taking Unithroid.
Among them, 26 people (3.18%) have Chest pain.

Among these 26 people:

How long have people been on Unithroid when they have Chest pain? *

What is the gender of people who have Chest pain when taking Unithroid? *

female: 88.46 %
male: 11.54 %

What is the age of people who have Chest pain when taking Unithroid? *

What are other drugs people take besides Unithroid? *

What are other side effects people have besides Chest pain? *

Heart Palpitations (feelings or sensations that your heart is pounding or racing): 10 people, 38.46%
Headache (pain in head): 6 people, 23.08%
Fatigue (feeling of tiredness): 6 people, 23.08%
Dyspnea (difficult or laboured breathing): 6 people, 23.08%
Dizziness: 5 people, 19.23%
Stress And Anxiety: 5 people, 19.23%
Hypoaesthesia (reduced sense of touch or sensation): 5 people, 19.23%
Nausea (feeling of having an urge to vomit): 4 people, 15.38%
High Blood Pressure: 4 people, 15.38%
Weight Decreased: 4 people, 15.38%

What are the existing conditions these people have? *

High Blood Pressure: 6 people, 23.08%
High Blood Cholesterol: 4 people, 15.38%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 3 people, 11.54%
Fibromyalgia (a long-term condition which causes pain all over the body): 2 people, 7.69%
Thyroid Diseases: 2 people, 7.69%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 2 people, 7.69%
Chronic Thyroiditis (long lasting inflammation of thyroid gland): 2 people, 7.69%
Diabetes: 2 people, 7.69%
Drowsiness: 2 people, 7.69%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 2 people, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Unithroid and have Chest pain?

- Check whether Chest pain is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Unithroid:

Unithroid (890 reports)

Chest pain treatments and more:

Chest pain (363,501 reports)

Browse all side effects of Unithroid:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Chest pain:

Chest pain (3,458 drugs)

Browse all the conditions that are associated with Chest pain:

Chest pain (4,889 conditions)

Related publications that referenced our studies

Pang, T., & Gudi, A., "Chest pain following the use of fluvoxamine in depression", Proceedings of Singapore Healthcare, 2018 Jan .
Pang, T., & Gudi, A., "Chest pain following the use of fluvoxamine in depression", Proceedings of Singapore Healthcare, 2018 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on levothyroxine sodium (the active ingredients of Unithroid) and Unithroid (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.