Upneeq and Nausea - a phase IV clinical study of FDA data

Summary:

Nausea is reported as a side effect among people who take Upneeq (oxymetazoline hydrochloride), especially for people who are female, 50-59 old, have been taking the drug for < 1 month also take Gabapentin, and have Eyelid ptosis.

The phase IV clinical study analyzes which people have Nausea when taking Upneeq. It is created by eHealthMe based on reports of 1,178 people who have side effects when taking Upneeq from the FDA, and is updated regularly.

What is Upneeq?

Upneeq has active ingredients of oxymetazoline hydrochloride. eHealthMe is studying from 1,180 Upneeq users. Check the latest studies of Upneeq.

What is Nausea?

Nausea (feeling of having an urge to vomit) is found to be associated with 3,881 drugs and 5,633 conditions by eHealthMe. Check the latest studies of Nausea.

On Jul, 14, 2026

1,178 people reported to have side effects when taking Upneeq.
Among them, 19 people (1.61%) have Nausea.

Among these 19 people:

How long have people been on Upneeq when they have Nausea? *

What is the gender of people who have Nausea when taking Upneeq? *

female: 84.21 %
male: 15.79 %

What is the age of people who have Nausea when taking Upneeq? *

What are other drugs people take besides Upneeq? *

Cyanocobalamin: 7 people, 36.84%
Gabapentin: 7 people, 36.84%
Acetaminophen: 5 people, 26.32%
Epinephrine: 5 people, 26.32%
Vitamin E: 5 people, 26.32%
Lidocaine: 5 people, 26.32%
Potassium: 4 people, 21.05%
Nasonex: 4 people, 21.05%
Meclizine Hydrochloride: 4 people, 21.05%
Meclizine: 4 people, 21.05%

What are other side effects people have besides Nausea? *

Dizziness: 9 people, 47.37%
Headache (pain in head): 8 people, 42.11%
Abdominal Discomfort: 5 people, 26.32%
Dehydration (dryness resulting from the removal of water): 5 people, 26.32%
Fatigue (feeling of tiredness): 5 people, 26.32%
Nausea And Vomiting: 5 people, 26.32%
Stress And Anxiety: 4 people, 21.05%
Hot Flush (sudden feelings of heat): 4 people, 21.05%
Herpes Virus Infection: 4 people, 21.05%
Indigestion: 4 people, 21.05%

What are the existing conditions these people have? *

Eyelid Ptosis (falling of the upper or lower eyelid): 5 people, 26.32%
Immunodeficiency Common Variable: 4 people, 21.05%
Cushing's Syndrome (obesity, a rounded face, increased fat): 3 people, 15.79%
Myasthenia Gravis (a chronic condition that causes muscles to tire and weaken easily): 2 people, 10.53%
Rashes (redness): 1 person, 5.26%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 1 person, 5.26%
Breast Cancer: 1 person, 5.26%
Bleeding Disorders: 1 person, 5.26%
Acne (skin problems that cause pimples): 1 person, 5.26%

* Approximation only. Some reports may have incomplete information.

Do you take Upneeq and have Nausea?

- Check whether Nausea is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Upneeq:

Upneeq (1,180 reports)

Nausea treatments and more:

Nausea (962,089 reports)

Browse all side effects of Upneeq:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Nausea:

Nausea (3,881 drugs)

Browse all the conditions that are associated with Nausea:

Nausea (5,633 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on oxymetazoline hydrochloride (the active ingredients of Upneeq) and Upneeq (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.