Zetia and Clostridium difficile colitis - a phase IV clinical study of FDA data

Summary:

Clostridium difficile colitis is reported as a side effect among people who take Zetia (ezetimibe), especially for people who are female, 60+ old, have been taking the drug for 2 - 5 years also take Lasix, and have Gastroesophageal reflux disease.

The phase IV clinical study analyzes which people have Clostridium difficile colitis when taking Zetia. It is created by eHealthMe based on reports of 47,765 people who have side effects when taking Zetia from the FDA, and is updated regularly.

What is Zetia?

Zetia has active ingredients of ezetimibe. It is often used in high blood cholesterol. eHealthMe is studying from 49,113 Zetia users. Check the latest studies of Zetia.

What is Clostridium difficile colitis?

Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection) is found to be associated with 1,042 drugs and 1,782 conditions by eHealthMe. Check the latest studies of Clostridium difficile colitis.

On Jul, 14, 2026

47,765 people reported to have side effects when taking Zetia.
Among them, 26 people (0.05%) have Clostridium difficile colitis.

Could Zetia cause Clostridium difficile colitis?

Among these 26 people:

How long have people been on Zetia when they have Clostridium difficile colitis? *

What is the gender of people who have Clostridium difficile colitis when taking Zetia? *

female: 85 %
male: 15 %

What is the age of people who have Clostridium difficile colitis when taking Zetia? *

What are other drugs people take besides Zetia? *

What are other side effects people have besides Clostridium difficile colitis? *

Anaemia (lack of blood): 8 people, 30.77%
Diarrhea: 8 people, 30.77%
Nausea (feeling of having an urge to vomit): 7 people, 26.92%
Acute Kidney Failure: 6 people, 23.08%
Gastric Ulcer (stomach ulcer): 6 people, 23.08%
Hypotension (abnormally low blood pressure): 5 people, 19.23%
Gastrointestinal Haemorrhage (bleeding gastrointestinal tract): 4 people, 15.38%
Fatigue (feeling of tiredness): 4 people, 15.38%
Pain In Extremity: 4 people, 15.38%
Dizziness: 4 people, 15.38%

What are the existing conditions these people have? *

Diabetes: 5 people, 19.23%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 19.23%
Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 4 people, 15.38%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 4 people, 15.38%
Chronic Renal Failure (kidney failure): 4 people, 15.38%
Depression: 4 people, 15.38%
Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 3 people, 11.54%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 3 people, 11.54%
Asthma: 3 people, 11.54%
Fibromyalgia (a long-term condition which causes pain all over the body): 3 people, 11.54%

* Approximation only. Some reports may have incomplete information.

Do you take Zetia and have Clostridium difficile colitis?

- Check whether Clostridium difficile colitis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Zetia:

Zetia (49,113 reports)

Browse all side effects of Zetia:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Clostridium difficile colitis:

Clostridium difficile colitis (1,042 drugs)

Browse all the conditions that are associated with Clostridium difficile colitis:

Clostridium difficile colitis (1,782 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on ezetimibe (the active ingredients of Zetia) and Zetia (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.