Valacyclovir hydrochloride and Pneumothorax - a phase IV clinical study of FDA data

Summary:

Pneumothorax is reported as a side effect among people who take Valacyclovir hydrochloride (valacyclovir hydrochloride), especially for people who are male, 60+ old, have been taking the drug for 1 - 6 months also take Tramadol, and have High blood pressure.

The phase IV clinical study analyzes which people have Pneumothorax when taking Valacyclovir hydrochloride. It is created by eHealthMe based on reports of 12,770 people who have side effects when taking Valacyclovir hydrochloride from the FDA, and is updated regularly.

What is Valacyclovir hydrochloride?

Valacyclovir hydrochloride has active ingredients of valacyclovir hydrochloride. It is often used in herpes zoster. eHealthMe is studying from 12,929 Valacyclovir hydrochloride users. Check the latest studies of Valacyclovir hydrochloride.

What is Pneumothorax?

Pneumothorax (the presence of air or gas in the cavity between the lungs and the chest wall, causing collapse of the lung) is found to be associated with 1,233 drugs and 1,346 conditions by eHealthMe. Check the latest studies of Pneumothorax.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 27, 2026

12,770 people reported to have side effects when taking Valacyclovir hydrochloride.
Among them, 12 people (0.09%) have Pneumothorax.

Could Valacyclovir hydrochloride cause Pneumothorax?

Among these 12 people:

How long have people been on Valacyclovir hydrochloride when they have Pneumothorax? *

What is the gender of people who have Pneumothorax when taking Valacyclovir hydrochloride? *

female: 30 %
male: 70 %

What is the age of people who have Pneumothorax when taking Valacyclovir hydrochloride? *

What are other drugs people take besides Valacyclovir hydrochloride? *

Acyclovir: 5 people, 41.67%
Allopurinol: 5 people, 41.67%
Prednisone: 5 people, 41.67%
Tramadol: 5 people, 41.67%
Omeprazole: 4 people, 33.33%
Meropenem: 4 people, 33.33%
Cyclophosphamide: 4 people, 33.33%
Tamsulosin Hydrochloride: 4 people, 33.33%
Bisoprolol Fumarate: 3 people, 25.00%
Dexamethasone: 3 people, 25.00%

What are other side effects people have besides Pneumothorax? *

Dyspnea (difficult or laboured breathing): 6 people, 50.00%
Hypotension (abnormally low blood pressure): 4 people, 33.33%
Septic Shock (shock due to blood infection): 4 people, 33.33%
Sepsis (a severe blood infection that can lead to organ failure and death): 4 people, 33.33%
Fever: 2 people, 16.67%
Bronchopulmonary Aspergillosis (lung disorder caused by aspergillus fungi): 2 people, 16.67%
Death: 1 person, 8.33%
Graft Versus Host Disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body): 1 person, 8.33%
Fatigue (feeling of tiredness): 1 person, 8.33%
Fall: 1 person, 8.33%

What are the existing conditions these people have? *

High Blood Pressure: 5 people, 41.67%
Urosepsis (secondary infection that occurs when a urinary tract infection spreads to the bloodstream): 4 people, 33.33%
Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 4 people, 33.33%
Indigestion: 4 people, 33.33%
Enlarged Prostate: 4 people, 33.33%
Spinal Pain (pain in spine): 4 people, 33.33%
Aspergillosis (an infection caused by a fungus called aspergillus): 2 people, 16.67%
Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 2 people, 16.67%
Cytokine Release Syndrome (immediate complication occurring with the use of anti-t cell antibody infusions): 2 people, 16.67%
Bone Marrow Conditioning Regimen: 2 people, 16.67%

* Approximation only. Some reports may have incomplete information.

Do you take Valacyclovir hydrochloride and have Pneumothorax?

- Check whether Pneumothorax is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Valacyclovir hydrochloride:

Valacyclovir hydrochloride (12,929 reports)

Pneumothorax treatments and more:

Pneumothorax (19,143 reports)

Browse all side effects of Valacyclovir hydrochloride:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Pneumothorax:

Pneumothorax (1,233 drugs)

Browse all the conditions that are associated with Pneumothorax:

Pneumothorax (1,346 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on valacyclovir hydrochloride (the active ingredients of Valacyclovir hydrochloride) and Valacyclovir hydrochloride (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.